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Completed

NCT Number: NCT05635721

Influence of Different Ankle Positions on Nerve Conduction Parameters of Deep Peroneal Nerve

BACKGROUND:

The deep peroneal nerve arises as a branch of the common peroneal nerve which courses around the neck of the fibula. The motor component of deep peroneal nerve is responsible for innervating the anterior compartment of the lower leg which includes the tibialis anterior, extensor hallucis longus, extensor digitorum longus, and peroneus tertius muscles.

Nerve conduction velocity shortly known as "NCV" tests are used determine the speed of the electrical signals moving along a specific peripheral nerve .This will be helpful in localizing the site of entrapment of peripheral nerves and useful for assessing both recovery and prognosis of any injury to peripheral nervesthere are numerous aspects that could influence nerve conduction study.

Although changes in joint position have been reported in several studies to affect nerve conduction velocity of peripheral nerves. the effect of changing ankle joint position on deep peroneal NCV has not been repor Purpose

This study will investigate the effect of different ankle positions on:

1. Deep peroneal nerve distal motor latency across ankle joint. 2. Deep peroneal nerve sensory onset latency across ankle joint

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Key information

Conditions

Healthy Subjects

Age range

20 year–40 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Mahmoud Salah

Aga, 055555, Egypt

About this study

31healthy subjects of both genders with age ranging from 20to 40years old were examined for motor distal latency and sensory onset latency at three different ankle positions :neutral,20degrees dorsiflexion and 40degrees plantar flexion

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Healthy subjects.
  • Age ranges from 20 to 40 years because longer latencies and slower nerve conduction velocity are seen significantly with increasing age.
  • All participants will be selected with body mass index (BMI) between 18.5 and 24.9kg/cm2 .

Exclusion criteria

  • Elderly subjects.
  • Pregnant women.
  • Subjects with history of or risk factors for peripheral nerve lesions.
  • Obese subjects.
  • Subjects with any foot deformity.
  • History of lower limb fractures.
  • History of surgery to lower limbs
  • Diabetic patients.
  • Patients with cardiovascular disorders.
  • Hypertensive patients.
  • Women wearing high heeled shoes.

Treatment and study plan

Primary outcomes

  1. Deep peroneal nerve motor distal latency

    Time frame: 30 minutes for each participant

    Motor distal latency: It is the time between the distal stimulus and the onset of compound muscle action potential(CMAP)at recording muscles

  2. Deep peroneal nerve sensory onset latency

    Time frame: 30 minutes for each participant

    : It is the time taken from the stimulus artifact to the initial negative deflection of the sensory nerve action potential (SNAP)

Sponsors and collaborators

Lead sponsor

Cairo University

Other

Registry information

Important dates

Study start
2022
Primary completion
2023
Study completion
2023
First posted
Dec 2, 2022
Registry last updated
Jan 30, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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