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NCT Number: NCT07339683

Influence of Cervical Stabilization Exercises on Neural Tissue Mechanosensitivity in Patients With Chronic Nonspecific Neck Pain

this study will be conducted to investigate the effect of cervical stabilization exercises on cervical pain intensity, upper limbs mechanosensitivity, cervicovertebral angle, and cervical proprioception in individuals with chronic nonspecific neck pain

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Key information

Age range

18 year–36 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

About this study

Neck pain is the sensation of discomfort in the neck area. Neck pain can result from disorders of any of the structures in the neck, including the cervical vertebrae and intervertebral discs, nerves, muscles, blood vessels, esophagus, larynx, trachea, lymphatic organs, thyroid gland, or parathyroid glands.Forward head posture (FHP) is one of the commonly recognized types of poor head posture in the sagittal plane in patients with neck pain. FHP has been defined as 'any alignment in which the external auditory meatus is positioned anterior to the plumb line through the shoulder joint, with a general prevalence of about 64% in both males and females.Several studies reported the effect of cervical stabilization exercises on pain, ROM and cranio-cervical angle in patients with chronic non-specific neck pain. No studies have been concerned with measuring mechanosensitivity as an indicator technique of the effect of different modalities on chronic non-specific neck pain. With the proposal of the cervical and scapulothoracic stabilization program for patients with chronic non-specific neck pain secondary to forward head posture deviations.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • participants with age range from 18 to 36 years and BMI from 25 to 30kg/m2 will be recruited
  • Participants having neck pain symptoms provoked by neck postures, neck movement, or palpation of the cervical musculature, for 3 months
  • Patients with a craniovertebral angle of less than 50º

Exclusion criteria

  • History of previous injury of the neck.
  • History of surgical intervention at the neck.
  • History of inflammatory joint disease affecting facet joints
  • participants with congenital disorders of the cervical spine.
  • participants who received pain medication or physical therapy for their neck pain during the last 3 months.

Treatment and study plan

cervical and scapulothoracic stabilization exercises.

Other

the patients will receive cervical and scapulothoracic stabilization exercises in the form of activation of deep cervical flexors in the first two weeks, followed by scapulothoracic muscles activation for the third and fourth weeks and finally group of exercises that emphasis on increasing difficulty and progress to quadruped and standing.

traditional therapy

Other

the patients will receive traditional therapy in the form of ultrasound, hot pack, cervical extensors stretching and deep flexor strengthening

Primary outcomes

  1. mechanosensitivity of upper limb nerves

    Time frame: up to 6 weeks

    A handheld algometer will be used to assess mechanosensitivity. To apply this test test, specific points on the peripheral nerve trunks of the tested upper limb nerves will be identified through manual palpation, being easily accessible by the probe of the algometer and as they are commonly used sites of peripheral nerves' palpation with moderate inter-tester reliability. The supine lying posture will be assumed to test median and ulnar nerves, while sitting posture will be the choice for radial nerve. Median nerve will be located and tested in the antebrachial fossa just medial to the biceps brachii tendon. Ulnar will be tested in the cubital tunnel between humeral medial epicondyle and olecranon process, with the arm in 90º shoulder abduction as well as external rotation, and elbow flexion. Radial nerve palpation point lies between the middle and lower thirds of the humerus.

Secondary outcomes

  1. craniovertebral angle

    Time frame: up to 6 weeks

    craniovertebral angle will be assessed by Kinovia software. Forward head posture will be determined when the craniovertebral angle is below 50 degrees (normal value).

  2. pain intensity

    Time frame: up to six weeks

    Visual analogue scale is the most commonly used method for assessing pain intensity. The left most value on the 10-cm horizontal line used for visual analogue scale indicates a painless condition, which is represented by 0. The rightmost value is 10, which represents extreme pain. The subjects will be in a relaxed position then will give them the appendix which contains VAS and rate their feelings of pain on the line by themselves, thereby quantifying the pain

  3. cervical joint position error (cervical proprioception)

    Time frame: up to six weeks

    To evaluate the joint position error , the examiner will hold the subject's head and moving slowly to the target head position, which is 50% of the maximum CROM and hold there for a period of 3 s. The subjects then memorized that target position and then the examiner slowly brought the subject's head back to the neutral position. The subjects then will be advised to reach the target position actively by moving the head and when subject reached the target position the reposition accuracy error will determine in degrees. The examiner will evaluate JPE tests in sagittal (flexion, extension) and transverse plane (right and left rotation) directions. Each direction of JPE testing will be performed three times and the mean error of these trials will be used in the analysis

Study contacts

Contact information is provided by the study sponsor or research team.

nada zuhairy, phd

CONTACT

[email protected]

01014930018

Sponsors and collaborators

Lead sponsor

Cairo University

Other

Registry information

Acronym: NP

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Jan 14, 2026
Registry last updated
Jan 14, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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