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NCT Number: NCT07102082

Influence of Authorized Smokeless Tobacco Product Modified Risk Claims I: Consumer Product Demand

To explore consumer responses to the announcement and implementation of new modified risk claims for Copenhagen and General Snus (brands of smokeless tobacco (ST) products) using a series of complementary and innovative research activities and methods.

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Key information

Age range

21 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Roswell Park

Buffalo, New York, 14206, United States

Location status: Recruiting

About this study

Primary Objectives:

To assess the influence of smokeless tobacco products' modified risk claims on:

  • Product demand (measured as willingness to pay in USD) using an experimental auction approach; and
  • Perceived risk of tobacco-associated diseases as assessed using questionnaire-based measures.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Residing in one of the 8 counties of Western New York (Erie, Niagara, Cattaraugus, Chautauqua, Allegheny, Livingston, Genesee, Orleans, Wyoming).
  • Smoke cigarettes every day, at least 5 cigarettes per day, for at least 1 year.
  • Open to trying a non-combusted oral tobacco product.
  • Have access to a device (ie: computer/tablet/smartphone) with internet capabilities to participate in an online survey study.
  • Have the ability to read, write, and communicate in English.
  • Participant must understand the investigational nature of this study and an Independent Ethics Committee/Institutional Review Board approved information sheet prior to receiving any study related procedure

Exclusion criteria

  • Plan to quit smoking in the next 30 days.
  • Use of smokeless tobacco at least weekly in the last 6 months.
  • Lifetime use (that is, ever used at any time prior to the study) of Copenhagen or General Snus.
  • Unwilling or unable to follow protocol requirements.
  • Pregnant or planning to become pregnant (by self report)

Treatment and study plan

Modified Risk - None

Behavioral

Participants view ads with no modified risk claim

Modified Risk Claim

Behavioral

Participants view ads with a modified risk claim

Primary outcomes

  1. Demand for cigarettes

    Time frame: After one session - 1 hour

    After watching a series of advertisements for oral smokeless tobacco products, participants will provide opinions of them, including likelihood of buying product.

  2. Increase in knowlege of tobacco-associated diseases

    Time frame: After one session - I hour

    multi item assessment questionnaires of perceived harm/risks from products

Study contacts

Contact information is provided by the study sponsor or research team.

Sponsors and collaborators

Lead sponsor

Roswell Park Cancer Institute

Other

Collaborators

  • National Cancer Institute (NCI)

Registry information

Official study title

Ifluence of Authorized Smokeless Tobacco Product Modified Risk Claims II: Laboratory Assessment of Sensory and Subjective Effect

Important dates

Study start
2025
Primary completion
2027
Study completion
2027
First posted
Aug 3, 2025
Registry last updated
Jun 1, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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