Induction of Ovulation Using Clomiphene Citrate and N-acetyl Cysteine Versus Letrozole

Infertility is defined as a couple's inability to become pregnant after one year of unprotected intercourse in women 35 years old and younger, and for six months in women over age 35 years. In any given year, about 15 percent of couples in North America and Europe who are trying to conceive are infertile

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Key information

Conditions

Infertility Genital Diseases Urogenital Diseases

Age range

18 year–40 year

Sex eligibility

Female

Study type

Interventional

Phase

Phase 3

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

All primary and secondary. Infertility due to anovulation

Exclusion criteria

Male factor infertility, tubal factor.
Endocrineopathy
Hypothyrodism
Morbid obesity
Under weight
Patient with previous surgery including drilling of ovary, Clomiphene Citrate resistant to ovulation.

Treatment and study plan

letrozole

Drug

oral tablets 5 mg

Clomiphene Citrate plus N acetyl cystine

Drug

Clomiphene Citrate 100 mg oral tablets+ N acetyl cystiene 600 mg

Primary outcomes

rate of ovulation

Time frame: 3 months

ultrasound evaluation

Sponsors and collaborators

Lead sponsor

Assiut University

Other

Registry information

Important dates

Study start: 2016
Primary completion: 2017
Study completion: 2017
First posted: Aug 7, 2017
Registry last updated: Aug 7, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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