Study to Evaluate Tezepelumab on Airway Inflammation in Adults With Uncontrolled Asthma (CASCADE)
NCT03688074
Asthma, Bronchial Diseases
Denver, Colorado, United States
View Trial DetailsNCT Number: NCT05685381
The aims of this project are twofold:
1. to characterize indoor air quality components obtained from apartments with gas stoves and open kitchens in a cohort of Black adults with uncontrolled asthma recruited from federally qualified health centers and enrolled in the parent study. 2. to conduct a comprehensive assessment of feasibility, implementation, and acceptability of the study.
Looking for future studies?
Notify Me18 year and older
All sexes
Observational
Sun River Health, Beacon, New York, United States
People spend as much as 90% of their time indoors, making indoor air quality (IAQ) particularly important to health. Many homes in New York City, particularly low-income housing, contain gas kitchen appliances, which generate fuel through the combustion of natural gas, generating indoor pollutants. Increasing evidence finds that even low levels of these pollutants are hazardous for human health. Those most vulnerable to ambient air pollution live in homes with gas appliances and inadequate ventilation. Moreover, individuals with pre-existing diseases like asthma are particularly susceptible to adverse health effects from poor IAQ, which gas stoves may exacerbate. This study addresses the important problem of uncontrolled asthma among a group at high risk for asthma and its adverse effects - Black adults who reside in homes with gas stoves and open kitchens. The investigator aims to characterize indoor air quality components in a cohort enrolled in the parent R01 (NCT05341726) and conduct a comprehensive assessment of feasibility including process, implementation and acceptability metrics. Identifying new targets for asthma self-management that could produce better health outcomes, thus addressing an important health inequity issue.
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
(participants):
Patient participants will
Exclusion criteria
(participants):
Time frame: Post-trial visit (up to 3 months after intervention completion)
The number of participants who complete the acceptability questionnaire. The acceptability questionnaire is a semi-structured interview at the time of indoor air quality sample retrieval and will be guided by the constructs of the Theoretical Framework of Acceptability (e.g., burden, user experience, attitudes, participation intentions).
Columbia University
Other
Contextualizing Asthma Self-Management With Measures of Indoor Air Quality for Black Adults With Uncontrolled Asthma
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
Published trials that share one or more normalized conditions with this study.
NCT03688074
Asthma, Bronchial Diseases
Denver, Colorado, United States
View Trial DetailsNCT02162576
Asthma, Bronchial Diseases
Louisville, Kentucky, United States
View Trial DetailsNCT00941577
Asthma, Bronchial Diseases
Hamilton, Ontario, Canada
View Trial DetailsNCT05341726
Asthma, Bronchial Diseases
Beacon, New York, United States
View Trial Details