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Recruiting

NCT Number: NCT02806388

Individualized Molecular Profiling for Allocation to Clinical Trials (IMPACT) Project

This study aims to screen tumor molecular profile for better selection of anticancer treatment, in particular, allocation to clinical trials if available.

Recruiting

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Key information

Conditions

Solid Tumor

Age range

12 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

National Cancer Centre, Singapore

Singapore

Location status: Recruiting

About this study

Molecular profiling will be performed on archival tumor tissue or freshly collected tumor tissue from re-biopsy. Blood, pleural fluid, FNA, and/or saliva may be collected to study the genetic makeup and also to compare the tumor molecular profile. Personalized therapy will be given based on molecular profile.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Confirmed histological diagnosis of solid tumor
  • Suitable for systematic treatment and clinical trials
  • ECOG (Eastern cooperative oncology group) performance status < 2
  • Able to provide tumor tissue for molecular profiling
  • Able to understand and sign the informed consent form

Exclusion criteria

  • None

Treatment and study plan

Primary outcomes

  1. The molecular and clinical epidemiology for cancer patients being considered for novel therapeutics

    Time frame: 5 years

Secondary outcomes

  1. The proportion of patients who have actionable alterations and enrol into clinical trials

    Time frame: 5 years

  2. The correlation of molecular profiles with clinical outcomes

    Time frame: 5 years

Study contacts

Contact information is provided by the study sponsor or research team.

Daniel SW Tan

CONTACT

[email protected]

+65 6436 8000

Sponsors and collaborators

Lead sponsor

National Cancer Centre, Singapore

Other

Registry information

Acronym: IMPACT

Important dates

Study start
2011
Primary completion
2026
Study completion
2027
First posted
Jun 20, 2016
Registry last updated
May 13, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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