Skip to main content
OpenTrials
Completed

NCT Number: NCT03751605

Indirect Measurement of Respiratory Quotient in Unipulmonary Ventilation.

The measurement of VO2 and VCO2 makes it possible to calculate the respiratory quotient (RQ) (VCO2 / VO2) which is a reflection of human energy metabolism and therefore of anaerobiosis. A study has been conducted in our department to demonstrate the ability of the indirectly measured respiratory quotient (RQ) from the inspired and exhaled breath analysis of the anesthetic respirator to predict the onset of anaerobic metabolism and postoperative complications in the operating room.

Unipulmonary ventilation is the rule in thoracic surgery: it improves surgical exposure and protects the operated lung.

However, no study has examined the impact of these mechanisms on the indirect measurement of RQ in unipulmonary ventilation. The main objective of our work is to validate indirect RQ measurement during unipulmonary ventilation. The secondary objective was to assess the predictability of postoperative complications of indirect QR.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Respiratory Quotient Measurement

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

CHU Amiens

Amiens, 80054, France

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age>18 years old
  • Adults admitted to the operating room for thoracic surgery requiring unipulmonary ventilation

Exclusion criteria

  • Cardiac surgery
  • Laparoscopy
  • Preoperative oxygen therapy

Treatment and study plan

unipulmonary ventilation

Procedure

observational study based on the computation of respiratory quotient in patient cohort treated by unipulmonary ventilation in routine thoracic surgery

Primary outcomes

  1. Indirect respiratory quotient

    Time frame: during surgery

Secondary outcomes

  1. occurrence of at least one post-operative complication

    Time frame: through study completion, an average of 6 months

    the aim is to predict the occurrence of at least one complication with the use of indirect respiratory quotient

Sponsors and collaborators

Lead sponsor

Centre Hospitalier Universitaire, Amiens

Other

Registry information

Official study title

Validation of the Respiratory Quotient Measurement Measured Indirectly in Unipulmonary Ventilation (UNIQ Study)

Important dates

Study start
2018
Primary completion
2019
Study completion
2023
First posted
Nov 23, 2018
Registry last updated
Mar 1, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.