Independent Effects of Visceral Adipose Volume and Density on Patient Survival in Peritoneal Dialysis

It was VAT volume predict patient outcome, while VAT density predicted baseline membrane function in PD patients and reflected peritoneal vascular density and local inflammation status.

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Key information

Conditions

Uremia End Stage Renal Disease on Dialysis Female Urogenital Diseases Female Urogenital Diseases and Pregnancy Complications Kidney Diseases Male Urogenital Diseases Urogenital Diseases Urologic Diseases

Sex eligibility

All sexes

Study type

Observational

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

The study included peritoneal dialysis patients follow up in our center who had an abdominal CT scan within 2 weeks before PD catheter incubation.

Exclusion criteria

Those with acute inflammation according to clinical signs, lab results or abdominal CT scan were excluded from the cohort.

Treatment and study plan

Primary outcomes

To evaluate the association between peritoneal membrane solute transfer rate and abdominal visceral adipose tissue density measured on CT

Time frame: from the baseline, 4 weeks before PD catheter insert surgery until patients quit PD or follow up up to 48 months

Sponsors and collaborators

Lead sponsor

RenJi Hospital

Other

Registry information

Important dates

Study start: 2015
Primary completion: 2023
Study completion: 2025
First posted: Jul 25, 2025
Registry last updated: Jul 25, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed