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OpenTrials
Completed

NCT Number: NCT03734146

Independent and Combined Effects of Aerobic and Resistance Training on Blood Pressure

We compared the effects of 8 weeks of aerobic exercise only, resistance exercise only, or a combination of both on blood pressure in overweight or obese middle-aged adults with elevated blood pressure. Participants engaged in supervised exercise sessions 3 times per week for 60 minutes each session. Outcomes were assessed at baseline and after the 8-week intervention. Extra-intervention physical activity and diet were also assessed.

Completed

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Key information

Age range

45 year–74 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Systolic/diastolic blood pressure of 120-159/80-99 mm Hg
  • Non-smoking
  • Overweight or obese, with a body mass index of 25-40 kg/m2
  • Inactive--not meeting the aerobic or resistance physical activity guidelines, which means engaging in less than 150 minutes/wk of moderate intensity aerobic exercise and less than 2 days per week of resistance training over the past 3 months.

Exclusion criteria

  • Unstable coronary heart disease or decompensated heart failure
  • Severe pulmonary hypertension or aortic stenosis
  • Acute myocarditis, endocarditis, pericarditis, or aortic dissection
  • Other medical condition that is life-threatening or that can interfere or be aggravated by the exercise training such as cancer, uncontrolled diabetes, severe pain or mobility limitations.
  • Premenopausal women or postmenopausal women taking hormonal replacement therapy
  • Pregnant women or anticipated pregnancy via IVF or other medical procedures during the course of the intervention

Treatment and study plan

Aerobic Exercise

Behavioral

180 minutes of moderate-vigorous intensity aerobic exercise per week

Resistance exercise

Behavioral

180 minutes of resistance exercise per week

Combined Aerobic and Resistance Exercise

Behavioral

180 minutes of exercise per week with 90 minutes per week coming from moderate-vigorous intensity aerobic exercise and 90 minutes per week coming from resistance exercise

Primary outcomes

  1. Change in resting blood pressure

    Time frame: Immediately before and after the 8 week intervention

    resting systolic and diastolic blood pressure

Sponsors and collaborators

Lead sponsor

Iowa State University

Other

Registry information

Acronym: ART-B

Important dates

Study start
2014
Primary completion
2014
Study completion
2014
First posted
Nov 7, 2018
Registry last updated
Nov 7, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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