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NCT Number: NCT07275281

Incidental Findings on Coronary Computed Tomography Angiography

Coronary CT angiography (CCTA) is increasingly used for ischemic heart disease diagnosis. The rising number of CCTA tests has led to a significant increase in the number of finding unexpected incidental extracardiac diseases.

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Key information

Conditions

Computed Tomography Arterial Occlusive Diseases Arteriosclerosis Cardiovascular Diseases Coronary Angiography Coronary Artery Disease Coronary Disease Heart Diseases Incidental Findings Myocardial Ischemia Vascular Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

About this study

The increasing utilization of coronary computed tomography (CT) angiography (CCTA) to diagnose and triage patients with suspected or known ischemic heart disease has led to a parallel increase in the frequency of incidental findings in the coronaries (nonatherosclerotic), noncoronary cardiac structures and noncardiac structures.

Studies have reported a prevalence of incidental findings on CCTA up to 40%. Most of these findings have no clinical relevance, but some have significant clinical implications in the care and prognosis of the patients.

We sought to assess the frequency of incidental findings on CCTA scans in consecutive studies performed in the past 5 years.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adult patients ho underwent CCTA

Exclusion criteria

  • None

Treatment and study plan

CCTA (Review of the scans)

Diagnostic Test

Reviewing coronary scans done in the past 5 years looking for findings other than atherosclerotic coronary artery disease.

Primary outcomes

  1. Non atherosclerotic coronary disease

    Time frame: BASELINE

    Findings other than coronary atherosclerotic disease: coronary bridge, coronary dissection, coronary embolism, and coronary fistula.

  2. Non coronary cardiac findings

    Time frame: BASELINE

    Findings include valve calcifications, left atrial appendage thrombus, patent foramen ovale and septal defects, pericardial effusion, LV clots, cardiac tumors.

  3. Non cardiac findings

    Time frame: BASELINE

    Non cardiac findings include: a. major vascular abnormalities in the aorta and the pulmonary arteries, b. pulmonary disease: masses, lymph nodes, granulomas, and pleural effusion, and c. non pulmonary findings in the diaphragm and the hepatobiliary tree.

Study contacts

Contact information is provided by the study sponsor or research team.

Musa Saadeh

CONTACT

065001000

Wasfi Alghween, MD

CONTACT

[email protected]

+96265001000

Sponsors and collaborators

Lead sponsor

Jordan Collaborating Cardiology Group

Other

Registry information

Official study title

Incidental Noncardiac Findings on Coronary Computed Tomography Angiography

Important dates

Study start
2026
Primary completion
2027
Study completion
2027
First posted
Dec 10, 2025
Registry last updated
Dec 30, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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