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Completed

NCT Number: NCT03297164

Incidence Rate of Heart Failure After Acute Myocardial Infarction With Optimal Treatment

The main purpose of this study is to build a multi-center, prospective and regionally representative acute myocardial infarction(AMI) cohort,and build a study platform for heart failure caused by AMI; To explore the 1 year incidence rate of heart failure after AMI given the optimized treatment and the treatment model affecting the incidence rate of heart failure, and finally to reduce the incidence rate of heart failure by 5%.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Beijing An Zhen Hospital, Capital Medical University, Beijing, Beijing Municipality, China

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About this study

the study aim to enroll 12000 acute myocardial infartion (AMI) patients, including ST-segment elevation myocardial infarction (STEMI) and non ST-segment elevation myocardial infarction (NSETMI), Patients were divided into two groups(optimized group and un-optimized group) according to treatment models they accepted in 20 reginally representative hosptials of China. whether optimizaed or not is judged by 4 four aspects,including emergency treatment procedure, pre-infusion medication, reperfusion strategy selection, and early rehabilitation after reperfusion.Patients were followed at 1 month, 6 months and 12 months. The physical condition and clinical events(heart failure, death, re-infarction, revascularization, apoplexy, malignant arrhythmias, bleeding events, other adverse events)were collected at follow up.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • age≥18 years
  • diagnosed acute myocardial infarction
  • signed the informed consent form

Exclusion criteria

  • AMI is caused by surgery, trauma, gastrointestinal bleeding or complications of PCI;
  • AMI occurred in patients who have been hospitalized for other reasons;
  • patients with previous history of chronic heart failure;
  • researchers judging that patient's compliance was poor and could not complete the study according to the requirements.
  • life expectancy is less than 12 months;
  • heart transplant patients;
  • patients with tumors;

Treatment and study plan

Primary outcomes

  1. incidence rate of heart failure

    Time frame: 12th month after diacharge

    incidence rate of heart failure of acute myocardial infarction at 12th month

Secondary outcomes

  1. MACCE rate

    Time frame: 12th month after diacharge

    the major adverse cardiac celebral events including death,reinfarction,

  2. bleeding rate

    Time frame: 12th month after diacharge

    the incidence rate of bleeding

  3. severe adverse drug reactions

    Time frame: 12th month after diacharge

    severe adverse drug reactions at 12th month

Sponsors and collaborators

Lead sponsor

Harbin Medical University

Other

Registry information

Official study title

One Year Incidence Rate of Heart Failure After Acute Myocardial Infarction With Optimal Treatment-A Prospective,Multicenter,Cohort Study

Important dates

Study start
2017
Primary completion
2020
Study completion
2021
First posted
Sep 29, 2017
Registry last updated
Oct 1, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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