Tomas Bata regional Hospital
Zlín, 76001, Czechia
Location status: Recruiting
NCT Number: NCT07022210
The perioperative period poses a heightened risk of complications for patients, including hypotension. While the issue of intraoperative hypotension is well-documented in medical literature, the occurrence and causes of hypotension in the post-anesthesia care unit often receive less attention. This phase of postoperative care, however, is vital for ensuring patient stability and preventing severe consequences. Failure to identify and manage a drop in blood pressure can lead to hypoperfusion of critical organs, increasing the risk of morbidity and mortality. The aim of this study is to examine the frequency of hypotension in the post-anesthesia care unit-defined as systolic blood pressure <90 mmHg or a drop of more than 20% from baseline-and to identify factors contributing to its development.
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Request Info18 year–105 year
All sexes
Observational
Zlín, 76001, Czechia
Location status: Recruiting
The perioperative period is a critical time for patients, marked by an increased risk of various complications, including hypotension. While intraoperative hypotension is extensively studied in medical literature, the occurrence and underlying causes of hypotension in the post-anesthesia care unit (PACU) often remain overlooked. This phase of postoperative care is essential for stabilizing the patient and preventing severe outcomes. A failure to identify and adequately address a drop in blood pressure during this time can result in hypoperfusion of vital organs, increasing the likelihood of morbidity and mortality.
Hypotension in the PACU is defined as a systolic blood pressure below 90 mmHg or a decrease exceeding 20% compared to the patient's baseline measurements. The aim of this research is to explore the prevalence of hypotension in the PACU and to analyze the factors contributing to its occurrence. By improving the understanding of this issue, the study seeks to enhance patient outcomes through timely identification and management of hypotension in this crucial phase of care.
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Time frame: 0. postoperative day
Hypotension is defined as systolic blood pressure <90 mmHg or a decrease of more than 20% from baseline values.
Time frame: 0. postoperative day
Duration of the surgical procedure as a risk factor for the development of postoperative hypotension. The duration will be recorded in minutes.
Time frame: 0. postoperative day
ASA classification as a risk factor for the development of postoperative hypotension.
ASA I: A normal healthy patient with no systemic disease. ASA II: A patient with mild systemic disease that does not limit daily activities (e.g., well-controlled diabetes or hypertension).
ASA III: A patient with severe systemic disease that limits daily activities but is not incapacitating (e.g., poorly controlled diabetes or hypertension, chronic obstructive pulmonary disease).
ASA IV: A patient with severe systemic disease that is a constant threat to life (e.g., unstable angina, symptomatic heart failure).
ASA V: A moribund patient who is not expected to survive without surgery (e.g., ruptured abdominal aneurysm).
Time frame: 0. postoperative day
The type of anesthesia used: general, regional, and/or peripheral nerve block.
Time frame: 0. postoperative day
Blood loss during the surgical procedure, as documented in the surgical protocol.
Time frame: 0. postoperative day
Fluid intake and output during surgery, measured in milliliters.
Time frame: 0. postoperative day
Surgical specialties: neurosurgery, urology, gynecology, abdominal surgery, orthopedics
Time frame: 0. postoperative day
Administration of a crystalloid or colloid bolus to augment intravascular volume.
Time frame: 0. postoperative day
In cases of severe hypotension, vasopressor administration (e.g., ephedrine, phenylephrine, norepinephrine) may be required to ensure adequate perfusion of vital organs.
Time frame: 0. postoperative day
Repeated blood pressure measurement every 5 minutes.
Time frame: 0. postoperative day
Continuous heart rate monitoring.
Time frame: 0. postoperative day
The Trendelenburg position (legs elevated above the head) can help increase venous return and consequently blood pressure. It will not be performed in surgeries involving the lower extremities.
Time frame: 0. postoperative day
If hypotension does not improve despite repeated therapeutic interventions, escalation of care to the ICU may be necessary.
Time frame: 0. postoperative day
Inadequate gastrointestinal perfusion can lead to nausea and vomiting, complicating the patient's recovery.
Time frame: 0. postoperative day
Oliguria is a medical term referring to low urine output, typically defined as producing less than 400-500 mL of urine per day in adults.
Anuria is a medical condition characterized by the absence or near absence of urine production, typically defined as less than 100 mL of urine per day.
Time frame: 0. postoperative day
The Glasgow Coma Scale (GCS) is a clinical tool used to assess a person's level of consciousness after a brain injury. It evaluates three responses: eye opening, verbal response, and motor response, with scores ranging from 3 (deep coma) to 15 (fully alert).
Time frame: 0. postoperative day
Will be assessed using oxygen saturation levels (SpO₂). Mild hypoxia: SpO₂ 90-94% Moderate hypoxia:r SpO₂ 75-89% Severe hypoxia: SpO₂ <75%
Time frame: 0. postoperative day
Lactic acidosis is a condition characterized by the accumulation of lactic acid in the bloodstream, leading to a decrease in blood pH. It can result from tissue hypoxia, impaired metabolism, or certain medical conditions.
Lactic acidosis is generally defined by a serum lactate concentration above 4 mmol/L. Mild elevations in lactate (hyperlactatemia) occur at levels above 2 mmol/L, but true lactic acidosis is diagnosed when lactate levels exceed 4 mmol/L
Time frame: 0. postoperative day
Syncope is a temporary loss of consciousness due to a sudden decrease in blood flow to the brain. It typically has a rapid onset, short duration, and spontaneous recovery
Contact information is provided by the study sponsor or research team.
Tomas Bata Hospital, Czech Republic
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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