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OpenTrials
Completed

NCT Number: NCT05381493

Incidence and Outcomes of Acute Kidney Injury in Trauma Patients Admitted to Critical Care

Acute kidney injury (AKI) is a common complication that increases lenght of stay and mortality in trauma patients admitted to the intensive care unit (ICU). The aim of this study is to identify the incidence and outcomes of trauma patients, defined by Kidney Disease Improving Global Outcomes (KDIGO) criteria, at single center level 3 ICU.

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Key information

Age range

18 year–97 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Süheyla Karadağ Erkoç

Ankara, 06230, Turkey (Türkiye)

About this study

Trauma can cause high mortality and morbidity by affecting different organ systems. Acute kidney injury (AKI) is a common complication in trauma patients admitted to the intensive care unit (ICU). Direct kidney injury, hypotension, hypoperfusion, rhabdomyolysis, abdominal compartment syndrome, sepsis and critical care medications are possible causes of AKI in trauma patients. The incidence of AKI can be up to 10%, and mortality rate up to 60-80% in trauma patients. Since AKI is not only a rare complication but also a risk factor for mortality in critically ill trauma patients, it is essential to establish a strategy to prevent AKI and related complications, to determine the incidence and risk factors of AKI, and to improve patients outcomes. Survivors of AKI may have variable recovery of kidney function and might prone to late morbidity and mortality. In this study incidence of AKI was defined using the KDIGO criteria according to the change of serum creatine levels.

171 all type of trauma patients admitted to level 3 ICU, from January 2014 to December 2018 included the retrospectve observational study. Demographic data, type of injury, rates of complications, risk factors for AKI, mortality, lenght of stay (LOS) in ICU were evaluated. Acute Physiology and Chronic Health Evaluation (APACHE II and IV) score, Simplified Acute Physiology Score (SAPS II and III), Glasgow Coma Scale (GCS), Injury Severity Score (ISS) and, Trauma Injury Severity Score (TRISS) were calculated on the day of admission. AKI was defined using the KDIGO criteria according to the serum creatinine. The SPSS 11.5 program was used for statistical analysis.

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • all type of trauma patients admitted to level 3 ICU, from January 2014 to December 2018

Exclusion criteria

-

Treatment and study plan

Primary outcomes

  1. Acute kidney injury in trauma patients

    Time frame: one week

    Kidney Disease Improving Global Outcomes (KDIGO) criteria

Sponsors and collaborators

Lead sponsor

Ankara University

Other

Collaborators

  • Ali Abbas Yılmaz
  • Bengi Şafak
  • Keziban Sanem Çakar Turhan
  • Mustafa Kemal Bayar
  • Mustafa Onur Karaca
  • Uğur Aydoğan

Registry information

Important dates

Study start
2021
Primary completion
2022
Study completion
2022
First posted
May 19, 2022
Registry last updated
May 19, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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