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NCT Number: NCT04074005

Incidence and Factors Involving Cesarean Delivery After Epidural Analgesia for Labor

The rate of cesarean delivery after epidural analgesia for labor has not been reported in our institute. The aim of this study is to elucidate incidence of cesarean delivery in parturient whom received epidural analgesia. Besides, factors associated with the rate of cesarean delivery were studied.

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Key information

Age range

18 year and older

Sex eligibility

Female

Study type

Observational

Primary location

Siriraj Hospital, Mahidol University

Bangkok, 10700, Thailand

About this study

Epidural analgesia with local anesthetic and opioid is the efficiently good method to relieve labor pain comparing with intravenous opioid analgesic. Many literatures reported effects epidural analgesia for labor eg. prolonging the duration of second stage of labor, increasing the rate of instrumental delivery: vacuum extraction and forceps assisting labor. Some papers revealed the increasing in the rate of cesarean delivery. The main reason is assume to be a failure to progress labor after epidural analgesia. However, the recent report from Cochrane database systematic review showed no relation of epidural analgesia for labor and the increasing in the rate of cesarean delivery. Various factors that may involve in the increasing in the rate of cesarean delivery including the dilatation of cervix at the time of insertion of epidural catheter, nulliparous, size of the fetus or motor weakness after receiving epidural medication.

The rate of cesarean delivery after epidural analgesia for labor has not been reported in our institute. The aim of this study is to elucidate incidence of cesarean delivery in parturient whom received epidural analgesia. Besides, factors associated with the rate of cesarean delivery were studied.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age>,= 18 years
  • Accept epidural analgesia for labor
  • ASA classification I-II

Exclusion criteria

  • Unable to communicate Thai

Treatment and study plan

Primary outcomes

  1. Incidence of cesarean delivery after epidural analgesia for labor

    Time frame: From epidural catheter insertion to delivery

    Rate of cesarean delivery after patients receive epidural analgesia for relieve labor pain

Secondary outcomes

  1. Factors affecting rate of cesarean delivery after epidural analgesia for labor

    Time frame: at the time epidural catheter insertion

    cervical dilatation before insertion epidural catheter (cm.)

  2. Efficacy of epidural analgesia for labor

    Time frame: before and after epidural catheter insertion

    pain score (verbal rating scale pain score)

  3. Side effects of epidural analgesia for labor: nausea and vomiting

    Time frame: From epidural catheter insertion to delivery

    nausea and vomiting (rating by patients: 0= no symptom, 1= nausea 2= vomiting)

  4. Side effects of epidural analgesia for labor: pruritus

    Time frame: From epidural catheter insertion to delivery

    pruritus (0=no, 1=yes)

  5. Side effects of epidural analgesia for labor: numbness of legs

    Time frame: From epidural catheter insertion to delivery

    numbness of legs (0=no, 1=yes)

  6. Side effects of epidural analgesia for labor: motor weakness

    Time frame: From epidural catheter insertion to delivery

    Rate motor weakness by Bromage score

Sponsors and collaborators

Lead sponsor

Mahidol University

Other

Registry information

Important dates

Study start
2020
Primary completion
2024
Study completion
2024
First posted
Aug 29, 2019
Registry last updated
Dec 22, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

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This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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