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NCT Number: NCT07382765

In This toGether R01

The goal of this study is to assess the effectiveness of the text-based ITG intervention to promote behaviors associated with HIV prevention amongst 18-22 year-olds in Uganda.

The main questions the study aims to answer are:

1. In a twelve-month period, does the intervention increase HIV testing and use of condoms?

a. How do the different interactive elements effect this? 2. How is effectiveness different for populations based on education, sex, and location (urban/rural)? Researchers will compare the control group, with no intervention, and the three combinations of the three intervention components: quiz questions, milestone badges, and access to on-demand advice.

Participants will receive the intervention via text messages and partake in the interactive elements listed above.

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Key information

Conditions

HIV

Age range

18 year–22 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Live in Uganda
  • Age 18 to 22
  • Have exclusive ownership of a cell phone
  • Have used text messaging for at least 6 months
  • Able to read English, Luganda, Runyakitara, or Luo

Exclusion criteria

  • Not participated in preliminary R34 study

Treatment and study plan

Level up quizzes

Other

Participant is given weekly quiz questions on that week's texted content

Badges

Other

Participants can earn badges by performing activities encouraged by program

On-demand advice

Other

Participants have access to ITGenie/Text Buddy, which responds to keywords with preset messages

Content

Other

Texted information about HIV prevention

Primary outcomes

  1. HIV testing

    Time frame: 12 months

    Binary variable. Was the participant tested for HIV during the study?

  2. Condom-protected sex acts

    Time frame: 12 months

    Self-reported count of condom-protected sex acts during study

Sponsors and collaborators

Lead sponsor

Center for Innovative Public Health Research

Other

Collaborators

  • Internet Solutions for Kids Uganda
  • Makerere University
  • National Institute of Mental Health (NIMH)

Registry information

Official study title

In This toGether: Testing a Population-based Text Messaging-based HIV Prevention Program for Young Adults Across Uganda

Acronym: ITG

Important dates

Study start
2026
Primary completion
2028
Study completion
2028
First posted
Feb 3, 2026
Registry last updated
Feb 3, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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