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OpenTrials
Completed

NCT Number: NCT00302874

In-Hospital Hyperglycemia: Effects of Treatment on Glycemic Control and Clinical Outcome

To improve glycemic control of inpatients admitted to the internal medicine wards, the researchers generated a protocol based on intensive insulin treatment for use in all inpatients with hyperglycemia.

The researchers hypothesize that intensive insulin treatment will improve the glycemic control and the outcome of hospitalized patients.

Study Information:

* All patients with a history of diabetes admitted to the internal medicine ward were enrolled in the study. * At baseline, demographic and clinical information were obtained, including information necessary to determine the severity of the illness. Venous capillary blood glucose levels were checked 4 times a day by glucometer. * During the pre-intervention period, patients were treated according to the common practice in the hospital without any intervention. The study team collected the baseline data on the glycemic control and treatment of patients admitted with hyperglycemia. * During the intervention period, the study team visited the ward daily and guided the medical staff as to the use of the treatment protocol. * During the post-intervention period, the study team collected the data without active intervention in the implementation of the protocol. * Data was collected on the mode of treatment and glycemic control of all hyperglycemic patients throughout the study. The incidence of hypoglycemia, complications (myocardial infarction, stroke, infections), mortality, transfer to intensive care unit (ICU), length of hospitalization, and disposition at discharge were noted.

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Key information

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Hadassah Medical Organization

Jerusalem, 91120, Israel

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • All patients admitted to the internal medicine ward with hyperglycemia

Exclusion criteria

  • Patients admitted due to hypoglycemia, hyperosmolar state, and ketoacidosis

Treatment and study plan

Implementation of a protocol for treatment of hyperglycemia

Behavioral

Primary outcomes

  1. Mean blood glucose during hospitalization

Secondary outcomes

  1. Hypoglycemic events

  2. Length of in-hospital stay

  3. Infections

  4. Complications (myocardial infarction, stroke)

  5. Disposition at discharge (home, nursing home)

Sponsors and collaborators

Lead sponsor

Hadassah Medical Organization

Other

Registry information

Important dates

Study start
2003
Study completion
2004
First posted
Mar 15, 2006
Registry last updated
Mar 26, 2007

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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