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NCT Number: NCT07377149

Improving the Quality of Coronary Artery Bypass Grafting

This is a healthcare quality improvement study focused on increasing the utilization of arterial grafts in isolated coronary artery bypass grafting (CABG). Evidence indicates that arterial grafts, compared with venous grafts, provide superior long-term patency, which are recommended to use by the clinical practice guidelines.

In hospitals where the use of the internal mammary artery as a graft is relatively low(<90%) among CABG patients, multiple interventions will be implemented to improve its adoption rate.

In hospitals where internal mammary artery graft utilization is already high(≥90%), various interventions will be introduced to promote the use of multiple arterial grafts (defined as the use of two or more arterial conduits).

The study targets healthcare professionals as the primary subjects of intervention, with no direct interventions applied to patients during the study period. Changes in the internal mammary artery graft utilization rate and the multiple arterial graft utilization rate before and after the intervention will serve as the primary endpoints for evaluating intervention effectiveness in the two types of hospitals, respectively.

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Key information

Conditions

Coronary Artery Bypass Grafting (CABG)

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Patients whose data used to monitor the quality

Inclusion criteria

Aged ≥ 18 years old； Indicated for CABG and undergoing CABG.

Exclusion criteria

History of prior CABG; Concurrent other cardiac surgeries on the day of CABG; Malignant tumor or life expectancy < 1 year;

  • 50% stenosis of left subclavian artery; Pregnant women; Individuals diagnosed with mental illness or cognitive impairment (International Classification of Diseases-10 codes F01-F99); Patients considered by the investigator to have other factors unsuitable for inclusion.

Treatment and study plan

Interventions for healthcare professionals in hospitals with low usage rates

Behavioral

Hospitals with low usage rates aim to improve internal mammary artery graft utilization through interventions including education, theoretical training, technical training, conference exchanges, and regular feedback on quality monitoring results.

Interventions for healthcare professionals in hospitals with high usage rates

Behavioral

Hospitals with already high usage rates focus on increasing multi-arterial graft usage rates through similar intervention methods such as education, theoretical training, technical training, conference exchanges focus on multi-arterial graft use. The usage rates of multi-arterial graft for each hospital will be regular feed backed.

Primary outcomes

  1. Hospitals with low usage rates of internal mammary artery: internal mammary artery graft utilization rate

    Time frame: Duration of hospital stay(from date of admission to date of discharge)

    Internal mammary artery graft utilization rate: the utilization rate of at least one internal mammary artery graft in patients received isolated coronary artery bypass grafting.

  2. Hospitals with high usage rates of internal mammary artery: multiple arterial graft utilization rate

    Time frame: Duration of hospital stay(from date of admission to date of discharge)

    Multiple arterial graft utilization rate: the utilization rate of two or more arterial conduits in patients received isolated coronary artery bypass grafting.

Secondary outcomes

  1. In-hospital all-cause mortality rate

    Time frame: Duration of hospital stay(from date of admission to date of discharge)

    The in-hospital all-cause mortality rate of patients received isolated coronary artery bypass grafting.

Study contacts

Contact information is provided by the study sponsor or research team.

Zhe Zheng, MD, PhD

CONTACT

[email protected]

+86 88396051

Sponsors and collaborators

Lead sponsor

China National Center for Cardiovascular Diseases

Other Gov

Collaborators

  • Central China Fuwai Hospital of Zhengzhou University
  • Chinese Academy of Medical Sciences, Fuwai Hospital
  • First Affiliated Hospital of Wenzhou Medical University
  • Guangdong Provincial People's Hospital
  • Ruijin Hospital
  • Shandong Provincial Hospital
  • The First Affiliated Hospital with Nanjing Medical University
  • The General Hospital of Northern Theater Command
  • Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
  • West China Hospital

Registry information

Official study title

Quality Improvement Intervention on Utilization of Arterial Grafts for Coronary Artery Bypass Grafting

Acronym: CABG Quality

Important dates

Study start
2026
Primary completion
2029
Study completion
2029
First posted
Jan 29, 2026
Registry last updated
Jan 29, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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