Completed

NCT Number: NCT00235027

Improving Safety By Computerizing Outpatient Prescribing

Patient safety is at the forefront of critical issues in health care. Medications are the single most frequent cause of adverse events, and in the inpatient setting adverse drug events (ADEs) are common, expensive, injurious to patients, and often preventable. Relatively little, however, is known about the frequency of ADEs in the ambulatory setting, how to monitor for outpatient ADEs, or on the impact of prevention strategies such as computerization of prescribing supplemented by decision-support.

Completed

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Key information

Conditions

Impact of Electronic Prescribing on Medication Safety

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Regenstrief/Indiana University, Indianapolis, Indiana, United States

About this study

Specific Aim 1: Increase routine identification of outpatient adverse drug events (ADEs) through development of a computerized ADE detection monitor.

Specific Aim 2: Use basic computerized outpatient prescribing to reduce preventable ADEs in a diverse array of outpatient settings.

Specific Aim 3: Use advanced decision-support within computerized prescribing to reduce the frequency of preventable ADEs, medication errors, and potential ADEs.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

At Brigham & Women's Hospital, clinics utilizing the electronic medical record will be included. At Regenstrief, any clinic that has access to their electronic medical record will be utilized.

For the impact of basic decision support, clinics were not randomized
For impact of advanced decision support, clinics were randomized to receive the intervention

Exclusion criteria

Clinics not using electronic medical records

Treatment and study plan

Adverse Drug Event Monitoring

Other

The intervention in this study is the presentation of medication safety alerts in the electronic medical record to improve patient outcomes and safety.

Primary outcomes

Preventable Adverse drug events

Time frame: 8/5/2004 - 1/5/2005

Data were electronically collected each time a physician entered a prescription that triggered an alert related to medication safety.

Secondary outcomes

Total adverse drug events, medication errors

Time frame: 1/15/2001 - 5/15/2001

Sponsors and collaborators

Lead sponsor

Agency for Healthcare Research and Quality (AHRQ)

Fed

Registry information

Important dates

Study start: 2000
Primary completion: 2010
Study completion: 2010
First posted: Oct 10, 2005
Registry last updated: Jul 21, 2015

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.