Improving Metabolic & Mental Health in Female Healthcare Shift Workers

Clinical assessments will include DEXA, phlebotomy, questionnaires, and stool collection, which will be completed at weeks 0, 8, and 16 to assess changes in metabolic health and quality of life. Four days of 24-hour dietary recalls will be collected at baseline, and weeks 4, 8, 12, and 16. Garmin Vivofit4 activity trackers will be provided to all participants at baseline, and participants will be reminded to sync the devices once weekly at minimum.

During the 8-week intervention phase, participants will receive guidance on when and what to eat and when to sleep and be physically active. Additionally, participants will be provided with whey protein isolate powder and grain-based snack bars to be consumed primarily during work shifts. Lean body mass (kg) will be used to prescribe total caloric (~30kcal/kg lean mass) and protein (2g/kg lean mass) needs and sleep/rest goals will be 6-8 hours per 24 hour "day."

Inclusion criteria

• Female
• 18-50 years old
• BMI between 27 and 40 kg/m2
• >6 months in current predominantly night shift (average 30+ hours/week) schedule
• Can read and speak English
• Willing to correspond with study staff using smartphone technologies

Exclusion criteria

• Pregnant or undergoing hormonal treatment for fertility
• Major changes in any prescription medications within 3 months
• Major surgeries in last 3 months
• Diagnosis of Type 2 Diabetes or other major endocrine diseases
• Diagnosed food allergies or significant dietary limitations
• Currently engaged in intensive weight loss program
• Minimal medically necessary radiation exposure within the last year