Faculty Of Oral & Dental Medicine - Cairo University
Giza, EL Menial, 12613, Egypt
NCT Number: NCT07205640
Tooth extraction may be an unpleasant and painful experience for children, Post-extraction wound healing. Low-level laser therapy (LLLT) is a widely used adjuvant treatment for wound healing, resulting in both an increase in cell number and an increase in cell metabolism. HA it is an important component of the extracellular matrix and a constituent of the neural, connective, and epithelial tissues.
Trial opening soon.
Get Notified6 year–10 year
All sexes
Interventional
Not applicable
Giza, EL Menial, 12613, Egypt
Tooth extraction may be an unpleasant and painful experience for children. Pain felt during dental treatment, especially tooth extraction, is the most common complication. Pain management during and after tooth extraction is part of behavioral guidance, especially in pediatric patients.
Post-extraction wound healing and pain perception are related to hostrelated factors such as the patient's immune system, the use of painkillers and antibiotics, the presence of infection in the region, and the atraumatic nature of the procedure. Low-level laser therapy (LLLT) is a widely used adjuvant treatment for wound healing. It is based on the idea that exposure to a specific wavelength can alter cellular behavior, resulting in both an increase in cell number and an increase in cell metabolism. Aside from not having any negative effects, LLLT is an a thermic, photobiological, and nondestructive therapy approach.
HA it is an important component of the extracellular matrix and a constituent of the neural, connective, and epithelial tissues. Among the many biological effects of HA are its functions in cell differentiation, wound healing, inflammation, embryological development, and viscoelasticity.
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
A 980 nm diode laser will be applied immediately after extraction of the first permanent molar. The laser will be used in continuous mode at 0.5 W, with a total energy of 300 J, applied for 60 seconds at three points around the extraction socket.
Hyaluronic acid gel will be applied directly into the extraction socket immediately after tooth removal.
Time frame: 7 days
Wound size unit of measure : mm (millimeters) (mesiodistal and buccolingual dimension of each socket).
Time frame: Day 0, Day 3, and Day 7 post-extraction.
Gingival color assessed using the Landry, Turnbull, and Howley Index (normal vs inflamed).
Unit of Measure: Binary (normal / inflamed)
Time frame: Day 0, Day 3, and Day 7 post-extraction.
Presence or absence of bleeding when palpating the extraction site.
Unit of Measure: Binary (yes / no)
Time frame: Day 0, Day 3, and Day 7 post-extraction.
Presence or absence of pus at the extraction site.
Unit of Measure: Binary (yes / no)
Time frame: Immediately after intervention (Day 0).
Pain assessed using Wong-Baker Faces Pain Rating Scale (0 = no pain, 10 = worst pain).
(0 = no pain, 10 = worst pain). Higher scores indicate worse outcomes.
Contact information is provided by the study sponsor or research team.
Mona Ali Abd Elhafiz, BDS
CONTACT
Mona Ali AbdelHafiz, BDS
CONTACT
Cairo University
Other
Effect of Low-Level Laser Therapy Versus Hyaluronic Acid on Wound Healing After First Permanent Molar Extraction in Children.
Acronym: LLLT vs HA
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
Published trials that share one or more normalized conditions with this study.
NCT06520501
Body Weight, Mesh
View Trial DetailsNCT06520527
Body Weight, Mesh
Palangkaraya, Central Kalimantan, Indonesia
View Trial DetailsNCT07605377
Inguinal Hernia Unilateral, Mesh
Antalya, Turkey (Türkiye)
View Trial DetailsNCT07386067
Hernia, Hernia, Abdominal
Zagazig, Egypt
View Trial Details