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Completed

NCT Number: NCT01074827

Improving Gait in Multiple Sclerosis (MS) - Strength Training or Treadmill Walking?

The objective of this study is to evaluate the effect of strength training for the lower extremities and treadmill training on walking ability in persons with Multiple Sclerosis. The study is a randomized control trial with two groups and the intervention is 8 weeks of intensive strength training or treadmill walking. Primary outcome measure is walking ability, secondary outcome measures are balance, work economy and strength.

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Key information

Conditions

Multiple Sclerosis Autoimmune Diseases Autoimmune Diseases of the Nervous System Demyelinating Autoimmune Diseases, CNS Demyelinating Diseases Immune System Diseases Nervous System Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

St. Olavs Hospital

Trondheim, 7006, Norway

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Diagnosed with Multiple Sclerosis,classified as relapsing remitting,or primary/secondary progressive
  • Expanded Disability Status Scale (EDSS)score of ≤ 6
  • Reduced walking ability (subjectively experienced)

Exclusion criteria

  • persons with a level of ataxia, clinically assessed, that would affect their ability to perform the training.
  • spasticity requiring stretching og treatment with baclofen.
  • Other, not MS-related, conditions affecting walking ability.

Treatment and study plan

Strength training and treadmill training

Other

Eight weeks of intensive strength training or treadmill training

Primary outcomes

  1. Walking ability

    Time frame: 8 weeks

Secondary outcomes

  1. Strength

    Time frame: 8 weeks

  2. Work economy O2

    Time frame: 8 weeks

  3. Balance

    Time frame: 8 weeks

Sponsors and collaborators

Lead sponsor

St. Olavs Hospital

Other

Collaborators

  • Helse Midt-Norge
  • Norwegian University of Science and Technology

Registry information

Official study title

Strength Training or Treadmill Walking? A Randomized Control Study on the Effect on Gait in Multiple Sclerosis

Important dates

Study start
2010
Primary completion
2011
Study completion
2011
First posted
Feb 24, 2010
Registry last updated
Jul 8, 2015

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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