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NCT Number: NCT07526480

Improving Dementia Care in Primary Practice

This clinical trial will evaluate a multi-level scalable intervention called Improving Dementia Care (IDC). The investigators hypothesize that IDC will increase dementia detection in patients with impaired cognition more than the control condition, Enhanced Usual Care (EUC), over 6 months.

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Key information

About this study

This pilot RCT (N = 80) will evaluate the feasibility and effectiveness of a new multi-level intervention-Improving Dementia Care (IDC)-which aims to increase detection of Alzheimer disease (AD) in older primary care patients with impaired cognition. In IDC, investigators will screen older primary care patients for subjective cognitive concerns and objective cognitive impairment on the Telephone Interview for Cognitive Status (TICS). To eligible patients, the research team will deliver AD Education and Personalized Decision Counseling-eliciting values and goals to reach informed, preference-based decisions on whether to have an AD evaluation. In IDC, investigators will also send to primary care physicians (PCPs) the TICS results and a smart order set (i.e., orders for AD-relevant lab and neuroimaging) via the electronic health record (EHR). The research team posits that IDC-a patient-level and PCP-level intervention-will increase AD detection more than Enhanced Usual Care (EUC), which is usual care enhanced with sending the TICS results and smart order set to the PCPs of controls-solely a PCP-level intervention. At 6 months, investigators will compare IDC's vs. EUC's effectiveness to increase rates of: 1) Incident cognitive diagnoses (e.g., Mild Cognitive Impairment, AD); 2) Orders for AD-relevant lab and neuroimaging studies, 3) Completed AD-relevant lab and neuroimaging studies; 4) Prescribed AD medications; and 5) Referrals to AD specialists, masked to treatment assignment.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • No previous diagnosis of mild cognitive impairment (MCI) or Alzheimer's disease (AD).
  • Have a scheduled PCP visit in the next 4-6 weeks
  • Have subjective cognitive impairment
  • Score ≥ 26 on the Telephone Interview for Cognitive Status (TICS)

Exclusion criteria

  • EHR evidence or previous cognitive evaluations, diagnosis of MCI or AD, or use of AD medications
  • TICS score of ≤ 11.00
  • Inability to provide informed consent

Treatment and study plan

Improving Dementia Care

Other

During a phone session, participants receive ADRD Education and Personalized Decision Counseling, which consists of eliciting values and goals to reach informed, preference-based decisions on whether to have an ADRD evaluation. Participants' primary care physicians are sent cognitive screening results and a smart order set (i.e., orders for ADRD-relevant lab and neuroimaging) via the electronic health record (EHR).

Other names: IDC

Enhanced usual care

Other

Usual care enhanced with notices sent to participants' primary care physicians with cognitive screening results and a smart order set (i.e., orders for ADRD-relevant lab and neuroimaging) via the electronic health record (EHR).

Other names: EUC

Primary outcomes

  1. Incident cognitive diagnoses.

    Time frame: 6 months

    Chart reviews will identify the number of patients with a new cognitive diagnosis in each arm.

Secondary outcomes

  1. Orders for Alzheimer's disease-relevant lab and neuroimaging

    Time frame: 6 months

    Chart reviews will identify the number of patients with a new relevant lab and imaging tests.

  2. Prescribed Alzheimer's disease (AD) medications.

    Time frame: 6 months

    Chart reviews will identify the number of patients with a new AD medications.

  3. Referrals to Alzheimer's disease specialists

    Time frame: 6 months

    Chart reviews will identify the number of patients with relevant referrals.

  4. Completed AD-relevant lab and neuroimaging studies

    Time frame: 6 months

    Chart reviews will identify the number of patients with completed orders.

Study contacts

Contact information is provided by the study sponsor or research team.

Nina Diamond, MPH

CONTACT

[email protected]

267-872-1302

Sponsors and collaborators

Lead sponsor

Thomas Jefferson University

Other

Collaborators

  • Independence Blue Cross

Registry information

Acronym: IDC

Important dates

Study start
2026
Primary completion
2027
Study completion
2027
First posted
Apr 13, 2026
Registry last updated
Apr 17, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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