Improving Antiretroviral Medication Adherence Among HIV-infected Youth: Phase I

This phase of the protocol focuses on setting up the infrastructure necessary for conducting the study, including hiring and training activities with study staff. This time will be spent conducting interviews and using these data to inform the development of the intervention protocol and adaptation of all Life-Steps intervention materials, including study assessment instruments, for HIV-infected youth.

The interview is a one-time event and will last for 1.5-2 hours. It has two components: a quantitative assessment and a qualitative discussion. After all participants have completed the informed consent and assent (if under the age of 18) processes, the research staff will administer a brief quantitative assessment that will ask questions related to demographics, medication adherence, sexual risk, substance use, and psychosocial condition. The second part of the interview will be an open discussion. The interviews will be conducted by a trained member of the research staff. The interviews will be informed by a pre-determined qualitative topic guide.

Phase I

Inclusion criteria

• Age 13 to 24 years
• HIV-infected and aware of HIV-infection status
• Currently taking antiretroviral therapy, has been prescribed antiretroviral therapy in the past 6 months, or a medical provider has recommended antiretroviral medications within the last 6 months
• Willing and able to provide informed consent or assent (if under the age of 18)

Exclusion criteria

• Not willing or able to provide informed consent or assent (if under the age of 18)
• Is dealing with a severe mental illness requiring immediate treatment (e.g. active psychotic episode) or a mental illness that would limit a participant's ability to engage with study protocol (e.g. dementia)
• Has severe cognitive limitations that would limit a participant's ability to comprehend the informed consent or assent.

Phase II

Inclusion criteria

• Age 13-24 years
• HIV-infected and aware of HIV-infection status
• Currently taking antiretroviral therapy
• Self-reported difficulties adhering to HIV medications in the past 3 months
• Self-identify as heterosexual or LGB
• Willing and able to provide informed consent/consent of parent/guardian if under the age of 18

Exclusion criteria

• Not willing or able to provide informed consent or assent (if under the age of 18)
• Is dealing with a severe mental illness requiring immediate treatment (e.g. active psychotic episode) or a mental illness that would limit a participant's ability to engage with study protocol (e.g. dementia)
• Has severe cognitive limitations that would limit a participant's ability to comprehend the informed consent or assent.