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OpenTrials
Completed

NCT Number: NCT02828085

Improvement of the Etiological Diagnosis of the Pericarditis

Pericardial syndrome includes pericardites acute pericardial effusion and cardiac tamponade, recurrent pericarditis squeezing chronic pericarditis. The etiologies are very numerous and can be classified as infectious, neoplastic, metabolic or systemic, toxic causes. Diagnosis is difficult, and 80% of etiologies remain classified idiopathic. In their laboratory to improve the diagnosis of this syndrome investigators have developed a strategy of systematic prescription of biological tests by kit. This prescription by 'kit' strategy proved its interest by comparison with an intuitive requirement of biological. In this study investigators want to improve the diagnostic causative of pericarditis by implementing a new diagnostic strategy. This new strategy includes (i) samples additional less invasive for the patient, the swab pharyngeal and nasal, (ii) the addition of at the outset of more effective diagnostic techniques: specific Polymerase Chain Reaction (PCR)

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Assistance Publique Hopitaux de Marseille

Marseille, 13354, France

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patient prescribed with a pericarditis kit for etiological diagnosis of a pericardial syndrome.
  • Adult patient (= or > 18 years old)
  • Patient who freely signed the informed consent form.
  • Patient affiliated to a health insurance regime

Exclusion criteria

  • Minor patient ( age <18 years)
  • Pregnant, parturient or breastfeeding woman
  • Adult patient incapable or unable to consent
  • Patient deprived of liberty under judgment
  • Person living in a health or social specialised structure
  • Person in vital emergency situation

Treatment and study plan

Nasal swab

Biological

Nasal swab will be performed in addition to the routine diagnosis visit in order to determine the diagnosis of infective pericardite with a more specific technique: PCR

Primary outcomes

  1. Percentage of pericarditis whose etiological diagnosis has been established.

    Time frame: 1 day

Secondary outcomes

  1. Identification of the detected emerging pathogens among infectious causesof pericarditis

    Time frame: 1 day

  2. Prevalence of the emerging pathogens: assessement of the percentage of emerging pathogens among the studied population

    Time frame: 1 day

Sponsors and collaborators

Lead sponsor

Assistance Publique Hopitaux De Marseille

Other

Registry information

Acronym: PERICARDITE

Important dates

Study start
2013
Primary completion
2019
Study completion
2022
First posted
Jul 11, 2016
Registry last updated
Apr 21, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.