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Completed

NCT Number: NCT03151252

Improvement of Foodallergy Diagnostic in Gastrointestinal Tract

Currently, diagnostic possibilities for the detection of food allergy in the gastrointestinal tract are scarce. The endoscopic segmental Lavage is the method of choice, but it´s controversial.

Additional to the endoscopic segmental lavage fluid a cytobrush is used for collecting the mucosa cells and biopsies are taken. Comparative to the Lavage specific IgE antibodies, Tumor necrosis factor- alpha, Eosinophilic cation protein and mastcell tryptase were measured.

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Key information

Conditions

Food Allergy Food Hypersensitivity Hypersensitivity Hypersensitivity, Immediate Immune System Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Department of Medicine 1, Hector Center for Nutrition, Exercise and Sports, Friedrich-Alexander-University Erlangen-Nuremberg

Erlangen, 91052, Germany

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • all patients with suspicion of food intolerance and confirmed food allergy

Exclusion criteria

  • pregnant and patients under allergy medication (antihistaminic, cortison)

Treatment and study plan

cytobrush

Diagnostic Test

During the endoscopic Investigation the mucosa cells were collected by brushing the colon via cytobrush.

Primary outcomes

  1. detection of specific IgE Antibodies in colon

    Time frame: 1 hour

Sponsors and collaborators

Lead sponsor

University of Erlangen-Nürnberg Medical School

Other

Registry information

Official study title

Improvement of Foodallergy Diagnostic in Gastrointestinal Tract With a New Kind of Sampling

Important dates

Study start
2014
Primary completion
2022
Study completion
2022
First posted
May 12, 2017
Registry last updated
Jul 5, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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