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OpenTrials
Completed

NCT Number: NCT02314234

Improvement of Facial Nerve Monitoring in Parotid Surgery by Sugammadex

To investigate the effectiveness of rapid reversal of rocuronium-induced neuromuscular block by sugammadex during IONM of facial nerve during parotid surgery

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Key information

Conditions

Injury to Nerve During Surgery

Age range

18 year–80 year

Sex eligibility

All sexes

Study type

Observational

Primary location

I-Cheng Lu

Kaohsiung City, 807, Taiwan

About this study

Intraoperative neuromonitoring (IONM) of facial nerve has been applied in identifying and preserving facial nerve during parotid surgery. In this setting, even a single dose of nondepolarizing muscle relaxant may lead to delayed and weakened electromyography (EMG) signal in facial nerve monitoring during parotid surgery. The aim of this study was to investigate the effectiveness of rapid reversal of rocuronium-induced neuromuscular block by sugammadex during IONM of facial nerve during parotid surgery

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • undergoing parotid surgery

Exclusion criteria

  • facial nerve injury, renal failure, liver cirrhosis, neuromuscular disease

Treatment and study plan

sugammadex (Bridion)

Drug

single dose of sugammadex at skin incision

Primary outcomes

  1. evoked EMG amplitude of facial nerve

    Time frame: up to first post-op day

Sponsors and collaborators

Lead sponsor

Kaohsiung Medical University Chung-Ho Memorial Hospital

Other

Registry information

Official study title

Influence of Sugammadex on Facial Nerve Monitoring in Parotid Surgery

Important dates

Study start
2012
Primary completion
2015
Study completion
2015
First posted
Dec 11, 2014
Registry last updated
Feb 25, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.