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NCT Number: NCT05285059

Implicit Learning in Epileptic Children

Epileptic children suffer from impairments in various learning and memory tasks. Yet, no study investigated implicit learning in epileptic children. Implicit learning is not only underlying motor skills acquisition, but also social and cognitive ones. Because acquisition of new skills is optimal during childhood, the study of implicit learning mechanism in children is of major importance. The present study will be the first to explore implicit learning mechanisms in children with epilepsy. Implicit learning mechanisms can be preserved or altered.

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Key information

Conditions

Epilepsy Brain Diseases Central Nervous System Diseases Nervous System Diseases

Age range

8 year–14 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Agathe Marcastel, PhD, Bron, France

Loading trial locations.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • For Patient group only: Children with epilepsy
  • For Control group only: Children without neurological, psychiatric or developmental impairments
  • For both groups: Parent or tutors agreement
  • For both groups: Affiliated to French social security

Exclusion criteria

  • Neurological impairments unrelated to epilepsy
  • Psychiatric impairments unrelated to epilepsy
  • Developmental impairments unrelated to epilepsy

Treatment and study plan

ASRT task

Behavioral

The ASRT (Alternating Serial Reaction Time) task is a computerized behavioral task measuring implicit learning. This task consists of 20 series of trials lasting 2 minutes each.

In each trial, a stimulus is displayed on the screen in one of the four possible predefined locations. The participant must press a button to indicate the position of the stimulus on the screen. Response content and response time are recorded.

At the end of every trial, the participant can take a break and resume the task whenever ready. The task lasts about 45 to 50 minutes.

Primary outcomes

  1. Response time

    Time frame: The day of the inclusion

    Response time (in milliseconds) recorded during the ASRT task

  2. Response accuracy recorded during the ASRT task

    Time frame: The day of the inclusion

    Response accuracy (percentage of correct answers)

Study contacts

Contact information is provided by the study sponsor or research team.

Marcastel Agathe, PhD

CONTACT

[email protected]

+33 4 27 85 60 40

Nemeth Dezso, Pr

CONTACT

[email protected]

+33 4 81 10 66 04

Sponsors and collaborators

Lead sponsor

Hospices Civils de Lyon

Other

Registry information

Acronym: IMPLICIT

Important dates

Study start
2023
Primary completion
2027
Study completion
2027
First posted
Mar 17, 2022
Registry last updated
May 7, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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