MORE
BehavioralMORE plus TAU
NCT Number: NCT06032559
This hybrid implementation-effectiveness trial will evaluate Mindfulness-Oriented Recovery Enhancement (MORE) for patients with opioid use disorder receiving methadone treatment (MT). The investigators will also assess barriers and facilitators to integrating MORE into methadone treatment, and evaluate the impact of a sustainable train-the-trainer model on provider burden, intervention fidelity, intervention engagement, and outcomes. Participants will be assigned to a higher intensity MORE implementation strategy, a minimal intensity implementation strategy consisting of a simple, scripted mindfulness practice (SMP) extracted from the MORE treatment manual with minimal training and feedback and no supervision, or methadone treatment as usual (TAU). We aim to:
* Examine barriers and facilitators to the implementation of MORE and SMP in MT and evaluate strategies for optimizing training, fidelity, and engagement. * Evaluate the effectiveness and treatment fidelity of a higher intensity MORE implementation strategy versus a lower intensity, scripted mindfulness practice (SMP) implementation strategy as an adjunct to methadone TAU or methadone TAU, only. Outcomes include opioid and other drug use, craving, MT discontinuation, depression, anxiety, and physical pain (secondary outcomes) than patients randomized to TAU.
Interested in participating?
Request Info18 year and older
All sexes
Interventional
Phase 3
Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey, United States
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
MORE plus TAU
SMP plus TAU
TAU only
Time frame: Baseline through 52 weeks
mber of days of drug use as measured by self-reported days of use and biochemically verified use via drug screen.
Time frame: Baseline through 52 weeks
Chronic pain measured by the Brief Pain Inventory Short Form (range 0-10, with higher scores indicating worse pain).
Contact information is provided by the study sponsor or research team.
Eric Garland, PhD
CONTACT
Nina Cooperman, PsyD
CONTACT
Rutgers, The State University of New Jersey
Other
Implementation and Effectiveness of Mindfulness Oriented Recovery Enhancement as an Adjunct to Methadone Treatment for Opioid Use Disorder and Chronic Pain
Acronym: IMPOWR-MORE
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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