Impaired Vigilance, and Its Effects on Cognition and Behavior

Fifty healthy, young participants (10 male, 40 female) completed two 3-hour study sessions that were at least five days apart. The first session was a baseline. The sleep intervention took place on the night prior to Session 2, where the amount of time in bed was manipulated to be 60-130% of the individual's habitual sleep time. Within both sessions, subjective (Stanford Sleepiness Scale, SSS) and objective (Psychomotor Vigilance Test, PVT) alertness were measured. During the middle of each session, a 40-minute ad libitum meal opportunity allowed participants to eat from eight different food items. Food healthfulness, caloric density, distribution and number of calories were measured and compared to alertness levels.

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Key information

Conditions

Sleep Deprivation Behavior Behavior, Animal Dyssomnias Feeding Behavior Mental Disorders Nervous System Diseases Neurologic Manifestations Pathological Conditions, Signs and Symptoms Signs and Symptoms Sleep Wake Disorders

Age range

18 year–45 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Age: 18-45 years
BMI: 20-29 kg/m²
Eat breakfast at least 5 days per week
Wake time occurs between 5&10AM at least 5 days per week
Time in bed for sleep between 5&10 hours at least 5 days per week

Exclusion criteria

Dietary restrictions that prohibit them from selecting one of the food choices offered in the study (e.g., gluten allergies, diabetes, vegan diet, dairy avoidance, allergies to the respective food choices available),
are currently on a calorie-restricted diet, or
are currently at a weight that is less than 20% of their highest weight within the last three years.
Participation in shift work within 7 nights of the experiment
Diagnosed as having severe sleep apnea syndrome, narcolepsy or chronic insomnia
Diagnosed as having an eating disorder
Active serious health condition
Regularly taking vigilance-related medication (e.g., ADHD prescribed medication)
Typically consume more than 600 mg of coffee or more than 10 cigarettes per day

Treatment and study plan

Time in bed

Behavioral

Habitual time spent in bed for the purpose of sleep was determined at baseline. This was used to calculated the experimental time in bed the subject was to spent on the one night prior to the second lab visit.

Primary outcomes

Total calories consumed

Time frame: 45 minutes

Total calories consumed during a 45 minute meal opportunity during the each of the two study sessions.

Secondary outcomes

Alertness

Time frame: 15 minutes

Objective alertness was determined during each of the two study sessions during a 15 minute test of sustained attention (Psychomotor Vigilance Task).

Sponsors and collaborators

Lead sponsor

Stanford University

Other

Registry information

Important dates

Study start: 2011
Primary completion: 2012
Study completion: 2012
First posted: Jun 30, 2015
Registry last updated: Jun 30, 2015

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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