Completed
NCT Number: NCT02005718
Impact of Vitamin D on Endothelial Function and Blood Biomarkers Including CD28 Null Cells in CKD
Vitamin D deficiency is common in CKD and assciated with CV complications. Endothelial dysfucntion is common in CKD and is a harbinger of atherosclerosis. The study investigated the impact of Vitamin D on endothelial fucntion and blood biomarkers in CKD.
Completed
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Notify MeKey information
Conditions
Age range
18 year–80 year
Sex eligibility
All sexes
Study type
Interventional
Phase
Phase 3
Who can participate
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
- CKD 3-4 Age 18-80
Exclusion criteria
- Recent MI, CVA, malignancy active infection active inflammation High calcium already on Viatmin D therapy
Treatment and study plan
Primary outcomes
-
Flow mediated dilation
Time frame: 16 weeks
Secondary outcomes
-
CD28 null cell frequency
Time frame: 16 weeks
-
Blood biomarkers of endothelial function and inflammation
Time frame: 16 weeks
Sponsors and collaborators
Lead sponsor
St George's, University of London
Other
Registry information
Official study title
Impact of Cholecalciferol on Endothelial Fucntion and Blood Biomarkers in Patients With Chronic Kidney Disease
Important dates
- Study start
- 2010
- Primary completion
- 2013
- Study completion
- 2013
- First posted
- Dec 9, 2013
- Registry last updated
- Dec 9, 2013
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.