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Recruiting

NCT Number: NCT07354048

Impact Of Thyroid Dysfunction on Liver Function Tests

This study aims to evaluate the effect of thyroid dysfunction on liver function tests.

Recruiting

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Key information

Age range

20 year–60 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Sohag University Hospital

Sohag, Egypt

Location status: Recruiting

Location contact

Magdy M Amin, Professor

CONTACT

01090801900

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • All patients between the ages of 20-60 years old either with Hypothyroidism or Hyperthyroidism (controlled on treatment or not) and firstly diagnosed Hypothyroidism or Hyperthyroidism.
  • Euthyroid controls (clinically healthy control subjects were recruited from the general population with the same socio-economic status with the subjects.)

Exclusion criteria

  • Patients aged < 20 years old.
  • Patients With Liver Disease.
  • Pregnant and lactating women.
  • Patients with severe infections or sepsis.
  • Patients with Heart Disease.
  • Patients who on drugs that can affect liver function such as phenothiazine, phenylbutazone, methyldopa, among others.

Treatment and study plan

Control Group

Other

Healthy people

Patients with hypothyroidism or hyperthyroidism that are controlled on treatment

Other

This group includes patients with hypothyroidism or hyperthyroidism that are controlled on treatment

Patients with hypothyroidism or hyperthyroidism that are not controlled on treatment

Other

This group includes patients with hypothyroidism or hyperthyroidism that are not controlled on treatment

Patients with hypothyroidism or hyperthyroidism that are firstly discovered

Other

This group includes patients with hypothyroidism or hyperthyroidism that are firstly discovered

Primary outcomes

  1. Measuring total bilirubin level in patients with thyroid dysfunction diseases

    Time frame: 1 months

    Collecting blood samples from the patients

Study contacts

Contact information is provided by the study sponsor or research team.

Omnia A Mohamed, Resident

CONTACT

[email protected]

01285252564

Usama M Abdel-Aal, Professor

CONTACT

Sponsors and collaborators

Lead sponsor

Sohag University

Other

Registry information

Official study title

Impact Of Thyroid Dysfunction on Liver Function Tests In Sohag University Hospital

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Jan 21, 2026
Registry last updated
Jan 21, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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