Department of Outpatient Care and Community Medicine, University Hospital of Lausanne
Lausanne, 1011, Switzerland
NCT Number: NCT03551340
Evaluation of the impact of the introduction of multiplex PCR panels on the clinical management of patients with gastroenteritis at the University Hospital of Lausanne, Switzerland.
Looking for future studies?
Notify Me18 year–100 year
All sexes
Observational
Lausanne, 1011, Switzerland
Gastrointestinal multiplex PCR panels have been introduced in clinical practice several years ago, but the impact on the management of patients is yet unknown. The investigators are interested to evaluate if the multiplex PCR panels introduced at the University Hospital of Lausanne in July 2017 modified the usual medical care and in particular the prescription of anti-infectious treatments. The high sensitivity of the multiplex PCR panels should allow a more precise diagnosis of the etiology of the gastrointestinal symptoms of the patients than the traditional methods of stool culture and microscopy. The investigators expect therefore to observe a modification of the proportion of patients receiving anti-infectious treatment, but it is uncertain if it will lead to an increase or a decrease in the use of antibiotics. On one hand antibiotics could be prescribed more often due to a greater and faster detection of enteropathogens. On the other hand antibiotics could be prescribed less often due to more precise diagnosis, showing that viruses and certain bacteria do not require antibiotic treatment.
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Ambulatory patients who consulted the University Hospital of Lausanne between July 2016 and May 2017, and were investigated by traditional methods (stool microscopy and culture).
Ambulatory patients who consulted the University Hospital of Lausanne between July 2017 and May 2018 and had stool investigations by a gastro-intestinal panel.
Exclusion criteria
Patients for whom there ia record in the file that they do not accept that their data are used for research purposes.
The study will evaluate the change in medical management with the replacement of traditional stool investigations (microscopy and culture) by the new gastrointestinal multiplex PCR panels
Time frame: Within 1 week of availability of stool result
Number of patients receiving a prescription of antibiotics depending on the type of investigation
Time frame: 1 day
Number and types of pathogens identified depending on the type of investigation
Time frame: 1 month
Number of patients for whom one, two or more PCR tests were requested.
Time frame: 1 week
Number of patients who underwent additional investigations within 1 week after reception of the results of the initial investigations
University of Lausanne Hospitals
Other
Impact of the Introduction of a Gastro-intestinal Panel by PCR on the Treatment of Patients With Gastroenteritis
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
Published trials that share one or more normalized conditions with this study.
NCT06331156
Digestive System Diseases, Gastroenteritis
Mianyang, China
View Trial DetailsNCT05972733
Digestive System Diseases, Gastroenteritis
Rolling Hills Estates, California, United States
View Trial DetailsNCT06025695
Digestive System Diseases, Gastroenteritis
Baoshan, China
View Trial DetailsNCT06007781
Digestive System Diseases, Gastroenteritis
Fukui-shi, Japan
View Trial Details