Impact of Sub-anesthetic Dose of Ketamine on Post Spinal Hypotension in Caesarean Delivery

The purpose of this study is to evaluate the effect of sub anesthetic dose of ketamine on vasopressor (Ephedrine) requirement to prevent maternal hypotension after spinal anesthesia in caesarean section.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Anesthesia

Age range

18 year–40 year

Sex eligibility

Female

Study type

Interventional

Phase

Phase 4

Primary location

Ain Shams University hospitals

Cairo, 11591, Egypt

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Physical status American Society of Anesthesiologist(ASA) I or II. Full term pregnancy

Exclusion criteria

,Pre-eclampsia.
Chronic hypertension.
Cardiovascular troubles.
any contraindications to spinal anesthesia as back infection , coaguolopathy , patient refusal

Treatment and study plan

ketamine

Drug

patients will receive sub- anesthetic dose of ketamine 0.5 mg/kg in 3 ml of isotonic saline after spinal anesthesia

Other names: general anesthetic

Isotonic saline

Drug

patients will receive 3 ml of isotonic saline after spinal anesthesia

Primary outcomes

incidence of hypotension

Time frame: 5 hours

after spinal anesthesia sub- anesthetic dose of ketamine will be given and blood pressure will be recorded every 2 minutes till delivery , every 5 minutes till end of surgery

Sponsors and collaborators

Lead sponsor

Ain Shams University

Other

Registry information

Official study title

Impact of Sub-anesthetic Dose of Ketamine on Post Spinal Hypotension in Caesarean Delivery :Prospective , Randomized Double- Blinded Study

Important dates

Study start: 2019
Primary completion: 2019
Study completion: 2019
First posted: Aug 10, 2018
Registry last updated: May 19, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed