Impact of Sperm DNA Integrity on In Vitro Cycles

Sperm DNA integrity will be measured via the Toluidine Blue Assay (TBA) for patients undergoing In Vitro Fertilization (IVF); the study will determine correlations, if any, between IVF success and sperm DNA integrity.

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Key information

Conditions

Male Infertility Abortion, Habitual Abortion, Spontaneous Female Urogenital Diseases and Pregnancy Complications Genital Diseases Genital Diseases, Male Infertility Infertility, Male Male Urogenital Diseases Pregnancy Complications Unexplained Infertility Urogenital Diseases

Sex eligibility

Male

Study type

Observational

Primary location

Center for Human Reproduction

Manhasset, New York, 11303, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

couple undergoing IVF at the Center for Human Reproduction
sperm sample given from partner (not a donor)

Exclusion criteria

low sperm concentration (<5 million/cc)
using a donor sample

Treatment and study plan

Primary outcomes

Pregnancy

Time frame: 9 months

detemining whether the sperm sample (tested for DNA integrity) used to insemenate IVF retrieved eggs, results in a live birth

Sponsors and collaborators

Lead sponsor

Northwell Health

Other

Registry information

Acronym: TBA on IVF

Important dates

Study start: 2010
Primary completion: 2013
Study completion: 2013
First posted: Nov 2, 2010
Registry last updated: Apr 11, 2014

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed