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OpenTrials
Completed

NCT Number: NCT02539264

Impact of Smoking, Benzodiazepine (BZD) Use and Obesity on Severe Obstructive Sleep Apnea (sOSA)

In this study the investigators will analyze the influence of smoking, benzodizepine use, and obesity among patients with severe Obstructive Sleep Apnea (sOSA).

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Key information

Conditions

Obstructive Sleep Apnea Apnea Behavior Body Weight Dyssomnias Nervous System Diseases Nutrition Disorders Nutritional and Metabolic Diseases Obesity Overnutrition Overweight Pathological Conditions, Signs and Symptoms Respiration Disorders Respiratory Tract Diseases Signs and Symptoms Sleep Apnea Syndromes Sleep Apnea, Obstructive Sleep Disorders, Intrinsic Sleep Wake Disorders Smoking

Sex eligibility

All sexes

Study type

Observational

About this study

This study is a retrospective study. Patients enrolled: all patients with a PSG (polysomnography) between 1st January 2014 and 30th June 2015.

First analysis: influence of smoking, benzodiazepine use, and obesity on the AHI (Apnea Hypopnea Index: the number of apnea and hypopnea per hour of sleep).

Second analysis: only among patients with sOSA: influence of smoking, benzodiazepine use, and obesity on sleep fragmentation and night oximetry.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • All patients registered for an overnight PSG at Clinique Saint-Luc of Bouge

Exclusion criteria

  • None

Treatment and study plan

Smoking

Other

Influence of smoking on parameters derived from overnight PSG

obesity

Other

Influence of obesity on parameters derived from overnight PSG

Benzodiazepine use

Other

Influence of benzodiazepine use on parameters derived from overnight PSG

Primary outcomes

  1. Apnea Hypopnea Index

    Time frame: 1 day

    Apnea Hypopnea Index (AHI) is defined as the number of apnea and hypopnea per hour of sleep. It is the major determinant of the severity of OSA.

Secondary outcomes

  1. Sleep fragmentation defined by the percentage of time spent in each of the four stades of sleep (Stade 1, Stade 2, Slow wave sleep and Rapid Eye Movements)

    Time frame: 1 day

    Are smoking and/or obesity a risk factor for sleep fragmentation?

  2. Time spent under 90% of SpO2 during the night

    Time frame: 1 day

    Are smoking and/or obesity a risk factor for oxygen desaturation (< 90% SpO2) during the night?

Sponsors and collaborators

Lead sponsor

Astes

Other

Registry information

Official study title

Impact of Smoking, BZD and Obesity on Severe Obstructive Sleep Apnea (sOSA)

Important dates

Study start
2014
Primary completion
2015
Study completion
2015
First posted
Sep 3, 2015
Registry last updated
Jan 6, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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