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Recruiting

NCT Number: NCT07489417

Impact of Sleep Restriction on Blood Pressure Reactivity

The purpose of the research study is to examine the effects of shortened sleep on blood pressure.

Recruiting

Interested in participating?

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Key information

Conditions

Age range

18 year–45 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

University of Missouri

Columbia, Missouri, 65211, United States

Location status: Recruiting

Location contact

Jacqueline Limberg

CONTACT

[email protected]

573-882-2544

Jacqueline Limberg

PRINCIPAL_INVESTIGATOR

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Healthy adult men and women
  • 18-45 years of age
  • BMI < 25 kg/m² (normal weight group) or ≥ 30 kg/m² (obesity group)
  • Non-pregnant, non-breastfeeding, and non-nicotine users
  • Self-reported history of normal sleep duration (7-9 hours/night) and bedtime prior to midnight
  • Premenopausal

Exclusion criteria

  • No acute or chronic conditions
  • Taking no medications known to affect sleep, autonomic, metabolic, or cardiovascular function
  • Self-reported history of irregular sleep
  • Self-reported history of hepatic, renal, pulmonary, cardiovascular, or neurological disease, stroke or neurovascular disease, bleeding/clotting disorders, sleep apnea or other sleep disorders, diabetes, history of alcoholism or substance abuse, major cardiovascular event or surgical procedure within the past three months, or hypertension

Treatment and study plan

Sleep Restriction

Behavioral

You will be asked to shorten your sleep to four hours.

Primary outcomes

  1. Mean Blood Pressure

    Time frame: Baseline and during the last 1-minute of stress

    Mean Blood pressure

Study contacts

Contact information is provided by the study sponsor or research team.

Jacqueline Limberg

CONTACT

[email protected]

1-573-882-2544

Sponsors and collaborators

Lead sponsor

University of Missouri-Columbia

Other

Registry information

Important dates

Study start
2026
Primary completion
2027
Study completion
2027
First posted
Mar 24, 2026
Registry last updated
Jul 28, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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