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Completed

NCT Number: NCT07356908

Impact of Sleep Related Breathing Disorders on Outcomes of Acute Pulmonary Embolism

This study aimsto compare short-termclinical outcomesand one-year recurrence rates in patients with acute pulmonary embolism with versus without sleep-disordered breathing, recruited from Alexandria MainUniversityHospital.

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Key information

Conditions

Pulmonary Embolism Apnea Cardiovascular Diseases Dyssomnias Embolism Embolism and Thrombosis Lung Diseases Nervous System Diseases Respiration Disorders Respiratory Tract Diseases Sleep Apnea Syndrome (OSAS) Sleep Apnea Syndromes Sleep Apnea, Obstructive Sleep Disorders, Intrinsic Sleep Wake Disorders Vascular Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Faculty of Medicine

Alexandria, Egypt, 11511

About this study

This prospective observational study will include consecutive adult patients admitted to the Chest Diseases Department and related units at Alexandria Main University Hospital (AMUH) with a diagnosis of acute pulmonary embolism confirmed by CT pulmonary angiography and followed up with sllep study to asses the effect of sleep related breathing disorderon the recurrence of emboli.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age≥18years.
  • Objectively confirmed acute pulmonary embolism by computed tomography pulmonary angiography (CTPA).
  • Hemodynamically stable or clinically stabilized within 72 hours of admission. .Ability to provide informed consent.

Exclusion criteria

.Known central sleep apnea without obstructive features. .Inabilityto undergo sleep study evaluation.

  • Pregnancy

Treatment and study plan

Polysomnography

Diagnostic Test

This prospective observational study will include consecutive adult patients admitted to the Chest Diseases Department and related units at Alexandria Main University Hospital (AMUH) with a diagnosis of acute pulmonary embolism confirmed by CTPA

Primary outcomes

  1. Pulmonary embolism recurrence

    Time frame: 12 months

    ocuurence of pulmonary embolism during the follow up period confirmed by CTPA

  2. Recurrence of Pulmonary Embolism

    Time frame: ONE YEAR

    occurence of objectively confirmed pulmonary embolism during the one t=year follow up period confirmed by CTPA

Sponsors and collaborators

Lead sponsor

Alexandria University

Other

Collaborators

  • University of Alexandria

Registry information

Official study title

Short- Term Outcome and One -Year Recurrence in Acute Pulmonary Embolism Patients With and Without Sleep - Disordered Breathing

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Jan 21, 2026
Registry last updated
Jan 21, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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