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Completed

NCT Number: NCT07026812

Impact of Screens on Children's Growth

Short stature is defined as a height less than -2 Standard Deviations (SD) for age and a slowing of growth velocity by a loss of 1 SD/year. The causes of short stature are multiple (chronic diseases, growth hormone deficiency, hypothyroidism, hyperadrenocorticism, genetic syndromes, etc.). However, nearly 30% are considered idiopathic, with no identified etiology (Naccache et al., unpublished).

Growth hormone (GH) is secreted in a pulsatile manner with maximum peaks primarily at night, raising questions about the relationship between sleep disturbances and short stature.

In children, one of the main causes of sleep disturbances in the digital age is screen use, which is becoming increasingly important, particularly in the pediatric population.

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Key information

Age range

6 year–16 year

Sex eligibility

All sexes

Study type

Observational

Primary location

University Hospital of Rouen

Rouen, 76031, France

About this study

During the night, physiologically, the retina, which no longer receives light signals, sends a message to the suprachiasmatic nucleus, the main key element of the internal clock, and to the pineal gland, which synthesizes melatonin, the sleep hormone. Exposing screens to blue light therefore disrupts melatonin secretion, which leads to a disruption of the circadian rhythm and therefore sleep. Note that this effect of light on melatonin secretion depends on the time of day of exposure, the intensity, and the duration. Thus, exposure to screens before bedtime can be responsible for a delay or even an absence of melatonin synthesis, particularly in the case of nighttime awakenings.

While many studies have examined the impact of screens on children's psychological balance, weight, etc., none, to our knowledge, has examined the potential impact of screens on children's height growth. Hypothesis of this project: 70% of GH synthesis takes place at night, a few minutes after entering slow-wave sleep, sleep disturbed by screens could mean a lower secretion of GH and consequently a delay in height growth.

The objective of this project is to evaluate the impact of screen consumption on sleep and the impact of sleep on idiopathic growth disorder.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Children aged 6 to 16 years old coming to the day hospital for a growth hormone stimulation test or an oral provocation test (without growth disorders)
  • Not opposed to participating in the study
  • Patients affiliated with the Social Security system

Exclusion criteria

  • Growth hormone deficiency confirmed by 2 tests
  • Hypothyroidism
  • Hypercorticism
  • All chronic diseases
  • Skeletal pathologies: Turner syndrome, constitutional bone disease Intrauterine growth retardation
  • Pubertal delay defined by absence of puberty onset >13 years in girls and 14 years in boys
  • Patient under guardianship

Treatment and study plan

Primary outcomes

  1. Screen consumption on sleep

    Time frame: At enrollment visit

    Evaluation of the Impact of Screen Consumption on Sleep by Answers to the Questionnaire Given to the Child and/or Parent(s) (Depending on Age)

  2. Screen consumption on sleep

    Time frame: At enrollment visit

    Sleep assessment by responses to the questionnaire given to the child and/or the parent(s) (depending on age) in order to assess the duration of sleep

  3. Screen consumption on sleep

    Time frame: At enrollment visit

    Evaluation of the Impact of Screen Consumption on Sleep by Answers to the Questionnaire Given to the Child and/or Parent(s) (Depending on Age) in Order to Evaluate child's physical activity

  4. Impact of sleep on idiopathic growth disorder

    Time frame: At enrollment visit

    Collection of auxological data at the time of the day hospital consultation (height) noted in the health record and/or in the hospital medical file

  5. Impact of sleep on idiopathic growth disorder

    Time frame: At enrollment visit

    Collection of auxological data at the time of the day hospital consultation (weight) noted in the health record and/or in the hospital medical file

  6. Impact of sleep on idiopathic growth disorder

    Time frame: At enrollment visit

    Collection of auxological data at the time of the day hospital consultation (age) noted in the health record and/or in the hospital medical file

Secondary outcomes

  1. Impact of screens on body size (BMI)

    Time frame: At enrollment visit

    Evaluation of the impact of screens on body size (BMI) by response to the questionnaire given to the child and/or the parent(s)

Sponsors and collaborators

Lead sponsor

University Hospital, Rouen

Other

Registry information

Acronym: ECROIPED

Important dates

Study start
2022
Primary completion
2024
Study completion
2025
First posted
Jun 18, 2025
Registry last updated
Jun 18, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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