Impact of Respiratory Allergy on Response to Initiation of Biotherapy in Severe Asthma in Adult Severe Asthmatic Patients Followed at Poitiers University Hospital on Biotherapy

The aim of this study is to take stock of the situation of adult patients with severe asthma on biotherapy, followed up at Poitiers University Hospital, and in particular to increase our knowledge of factors predictive of response to biotherapy. The main aim is to improve the management of adult severe asthma patients treated with biotherapy, according to their allergic status.

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Key information

Conditions

Severe Asthma Asthma Biotherapy Bronchial Diseases Hypersensitivity Hypersensitivity, Immediate Immune System Diseases Lung Diseases Lung Diseases, Obstructive Respiratory Allergy Respiratory Hypersensitivity Respiratory Tract Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Chu Poitiers

Poitiers, 86000, France

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Severe asthma patient on biotherapy
Age > or = 18 years
Follow-up at Poitiers University Hospital

Exclusion criteria

Absence of allergological assessment
Patient's refusal to participate in study

Treatment and study plan

search for respiratory allergies

Other

analyses in terms of biotherapy and respiratory allergy

Primary outcomes

Find out whether a positive respiratory allergy test influences the efficacy of one or more biotherapies

Time frame: 1 year

Secondary outcomes

analyze the allergological workup, particularly with regard to common pneumallergens

Time frame: 1 year
look at the response to the biotherapy used

Time frame: 1 year

Sponsors and collaborators

Lead sponsor

Poitiers University Hospital

Other

Registry information

Acronym: IARBASP

Important dates

Study start: 2024
Primary completion: 2025
Study completion: 2025
First posted: Apr 8, 2025
Registry last updated: Apr 8, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

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This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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