Impact of Radiotherapy on Survival in Breast Cancer Patients

In this study, using a large retrospective cohort, the investigators evaluate the impact of RT on disease-free survival and overall survival of patients with BC. The aim is to determine the true role of radiotherapy in improving patient outcomes and to provide a basis for designing more precise treatment strategies in the future.

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Key information

Conditions

Breast Cancer Breast Diseases Breast Neoplasms Neoplasms Neoplasms by Site Radiotherapy Skin Diseases Skin and Connective Tissue Diseases

Sex eligibility

Female

Study type

Observational

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

-BC patients diagnosed between January 1998 and February 2008 in the Motamed Breast Cancer Research in Tehran, Iran.

Exclusion criteria

Male patients.
Patients with missing LPFS and OS information (zero encounter/follow-up).

Treatment and study plan

Radiotherapy

Radiation

Radiotherapy after BCS surgery in accordance to standard breast cancer guidelines

Primary outcomes

Survival

Time frame: 25 years

Sponsors and collaborators

Lead sponsor

Motamed Cancer Institute

Other

Registry information

Official study title

Impact of Radiotherapy on Disease-Free and Overall Survival in Breast Cancer Patients: A Retrospective Cohort Study

Important dates

Study start: 1998
Primary completion: 2008
Study completion: 2025
First posted: Jun 8, 2026
Registry last updated: Jun 8, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed