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NCT Number: NCT05450172

Impact of Postoperative Transitional Pain on Recovery After Thoracic Surgery

Postoperative transitional pain corresponds to the pain occuring between acute postoperative pain and chronic postsurgical pain (defined as pain persisting for at least 3 months after surgery). We hypothesized that both trajectory and neuropathic component of transitional pain may influence the quality of recovery after thoracic surgery. To test this, we designed an observational study to identify risk factors for incomplete recovery assessed through the QoR-15 questionnaire.

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Key information

Conditions

Postoperative Recovery

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

CHU

Angers, 49933, France

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • adult patients
  • patients scheduled for thoracic surgery (thoracotomy or video-assisted thoracic surgery or surgery for thoracic outlet syndrome)
  • patients who do not object to the study

Exclusion criteria

  • patients non francophone
  • emergency surgery or revision surgery
  • patients already included in the study during the previous 6 months

Treatment and study plan

QoR-15 questionnaire

Other

The QoR-15 is a 15-item questionnaire on postoperative quality of recovery. The DN4 is a 10-item questionnaire on neuropathic pain. Both questionnaires will be given to the patients preoperatively, on postoperative days 2 and 3, and 1, 3 and 6 months after surgery.

Other names: DN4 questionnaire

Primary outcomes

  1. Impact of pain trajectory and neuropathic component of pain on quality of recovery.

    Time frame: 3 months after surgery.

    An incomplete recovery will be defined as a postoperative QoR-15 score of at least 8 points lower than the preoperative QoR-15 value. The association between both trajectory and neuropathic component of postoperative transitional pain and incomplete recovery will be evaluated.

Secondary outcomes

  1. Description of trajectory and neuropathic component of postoperative transitional pain.

    Time frame: Between postoperative day 2 and 3 months after surgery.

    To describe the trajectory and neuropathic component of postoperative transitional pain according to QoR-15 and DN4 successive values.

  2. Impact of the type of surgery on quality of recovery.

    Time frame: 3 months after surgery.

    To assess the impact of thoracotomy or video-assisted thoracic on quality of recovery.

  3. Impact of pain trajectory, neuropathic component of pain and type of surgery on chronic postsurgical pain prevalence.

    Time frame: 3 and 6 months after surgery.

    To assess the impact pain trajectory, neuropathic component of pain and type of surgery on chronic postsurgical pain prevalence.

  4. Predictive accuracy of neuropathic pain trajectory on incomplete recovery and chronic postsurgical pain prevalence.

    Time frame: 3 and 6 months after surgery.

    To assess the predictive accuracy of neuropathic pain trajectory on incomplete recovery and chronic postsurgical pain prevalence.

  5. Correlation between neuropathic componente of chronic postsurgical pain and quality of recovery.

    Time frame: 3 and 6 months after surgery.

    To assess the correlation between neuropathic componente of chronic postsurgical pain and quality of recovery.

Sponsors and collaborators

Lead sponsor

University Hospital, Angers

Other Gov

Registry information

Acronym: TRANSAT

Important dates

Study start
2022
Primary completion
2024
Study completion
2024
First posted
Jul 8, 2022
Registry last updated
Dec 30, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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