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Completed

NCT Number: NCT05034081

Impact Of Post-Bariatric Body Contouring Procedures on Patient Body Weight and Metabolism

Is post-bariatric body contouring surgery prevent weight regain or no, and what is the effect on the patient's Metabolism? Few literature studies report body contouring surgery to be positively associated with maintained weight loss after obesity surgery but the measures of outcomes are diverse, and the collective magnitude of such an association is unknown.

The changes in gastrointestinal hormones, adipokines, and cytokines as well as in hypothalamic neuropeptides and neurotransmitters resemble the changes observed in the anorexia/cachexia, suggesting that bariatric surgery triggers a catabolic state responsible for loss of appetite and prolonged body weight reduction.

Weight regain after gastric bypass surgery occurs in about half of all patients within 2 years. About 50% of patients eventually gain a little weight back after hitting their low point. We need a more thorough evaluation to determine what factors - medical, psychological, lifestyle - are involved in the weight gain. One of the factors that seem to be responsible for the degree and durability of weight loss is post-bariatric body contouring procedures. However, metabolic consequences of removing excess subcutaneous adipose tissue by body contouring procedures have to a lesser extent been explored

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Key information

Age range

20 year–60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Assiut University

Asyut, Asyut Governorate, 088, Egypt

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Post-bariatric (sleeve) patients will do body contouring surgery.
  • Post-bariatric patients has been stable within 5 kg for 3 months
  • Age between 20-60 years old.
  • patients use the determinant fixed diet.

Exclusion criteria

  • Age below 20 and above 60 years old.
  • Non-compliance with the fixed diet.
  • psychotic patients.
  • Female patients seeking pregnancy.
  • Endocrine causes of obesity.
  • Bariatric surgery other than sleeve.

Treatment and study plan

body contouring

Procedure

any post-bariatric body contouring surgery included

Primary outcomes

  1. Weight Changes by Kilograms

    Time frame: 6 months

    to know the effect of post-bariatric body contouring surgery in weight. Detect the weight cahnges of the patient 3 and 6 months after body contouring surgery and body mass index also measured

  2. Level of Tumor Necrotizing Factor Alfa in Blood

    Time frame: 6 months

    Its a clinical laboratory investigation will be done before the body contouring surgeries and 3 and 6 months after. Tumor necrotizing factor alfa increase afer bariatric surgery and we want to know if its complete on increasing after body contouring surgeries or decresae . Tnf-a is measured by pg/ml

  3. Level of BNP in Blood

    Time frame: 6 months

    Its a clinical laboratory investigation will be done before the body contouring surgeries and 3 and 6 months after. BNP highly increase with catabolism after bariatric surgery and we want to know the effect of body contouring surgeries in the level of BNP. BNP unit is pg/ml

  4. Level of High Sensitive CRP in Blood

    Time frame: 6 months

    Its a clinical laboratory investigation will be done before the body contouring surgeries and 3 and 6 months after. hsCRP increase with catabolism after bariatric surgery and we want to know the effect of body contouring surgeries in blood level of hsCRp. The unit of hsCRP is mg/dl.

Secondary outcomes

  1. Patient Satisfaction Score

    Time frame: 6 months

    From 1 to 5 .

    1 very dissatisfied 5 very satisfied Increase in number means increase satisfaction.

Sponsors and collaborators

Lead sponsor

Assiut University

Other

Registry information

Important dates

Study start
2021
Primary completion
2024
Study completion
2025
First posted
Sep 5, 2021
Registry last updated
May 1, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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