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Completed

NCT Number: NCT07727278

Impact of PharmaCloud on Pharmacist-Led Medication Reconciliation Efficiency and Error Detection Among Taiwanese Inpatients

Taiwan's National Health Insurance Administration PharmaCloud provides cross-institutional medication access to reimbursed medication records to support best possible medication history (BPMH) compilation. However, its utility among internal medicine inpatients, who typically present with complex regimens and frequent medication changes, remains understudied. This study aims to evaluate the impact of PharmaCloud integration on pharmacist-led medication reconciliation (MedRec) efficiency and error detection among internal medicine inpatients at both admission and discharge.

The non-randomized, single-center study was conducted from May to November 2024 at the Far Eastern Memorial Hospital in Taiwan. Internal medicine inpatients taking at least one pre-admission chronic medication were enrolled and assigned to standard medication reconciliation protocol (control) or PharmaCloud-integrated medication reconciliation (experimental). Best possible medication history compilation time was recorded across two stages: preparation and interview. Medication discrepancies were identified at admission and discharge and classified as intentional or unintentional.

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Key information

Conditions

Medication Reconciliation Best Possible Medication History Medication Discrepancy

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Far Eastern Memorial Hospital

New Taipei City, 220216, Taiwan

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age 18 years or older
  • Use of at least one pre-admission medication for a chronic disease

Exclusion criteria

  • If patient was discharged within 48 hours of admission
  • If patient was scheduled for surgery during their inpatient stay

Treatment and study plan

PharmaCloud-integrated medication reconciliation

Other

The intervention entailed supplementing in-house electronic medical record with data from PharmaCloud, a platform launched by Taiwan's National Health Insurance Administration to enable cross-institutional access to reimbursed medication records.

Primary outcomes

  1. Best possible medication history compilation efficiency

    Time frame: From patient's time of hospital admission to 72 hours post-admission.

    The first outcome measure was best possible medication history (BPMH) compilation efficiency, which was measured in minutes as three metrics: preparation time (stage 1), measured from the start of electronic medical record (EMR) and PharmaCloud review to the completion of the preliminary BPMH; interview time (stage 2), measured from the start to the end of the face-to-face interview; and total BPMH compilation time, the sum of stage 1 and 2.

Secondary outcomes

  1. Medication error detection rate

    Time frame: Admission: Unintentional discrepancies identified from patient's time of admission to 72 hours post-admission. Discharge: Unintentional discrepancies identified immediately prior to patient's departure from the facility.

    Medication error detection rate was defined as the proportion of participants with at least one identified unintentional discrepancy at either admission or discharge. All identified discrepancies were categorized as either intentional or unintentional, depending on whether or not the medication changes were consciously made by the prescribers, respectively.

Sponsors and collaborators

Lead sponsor

Far Eastern Memorial Hospital

Other

Collaborators

  • National Yang Ming Chiao Tung University

Registry information

Official study title

Impact of Integrating PharmaCloud on Pharmacist-Led Medication Reconciliation Efficiency and Error Detection Among Internal Medicine Inpatients: A Prospective Non-Randomized Study in Taiwan

Important dates

Study start
2024
Primary completion
2024
Study completion
2024
First posted
Jul 27, 2026
Registry last updated
Jul 27, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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