Impact of Perioperative Shedding of the Endothelial Glycocalyx on Short-term Postoperative Complication in Patients Undergoing Robot-assisted Esophagectomy

preoperative baseline serum levels of syndecan-1

blood concentration of syndecan-1 at the end of the surgery

blood concentration of syndecan-1 at 24 hours after surgery

Indicate if the patient had an unplanned invasive procedure after surgery. Examples includes return to the operating room for a redo surgical procedure, a percutaneous procedure performed at bedside or in the radiology suite, a tracheostomy, and wound opening at bedside. Exclusions: postoperative toilet bronchoscopy, central venous access, arterial line placement, foley catheter placement.

Indicate if the patient had an anastomotic leak following esophageal surgery.

Indicate whether the patient experienced respiratory failure in the postoperative period requiring mechanical ventilation and/or reintubation.

Indicate if the patient initially was ventilated greater than 48 hours in the postoperative period. If the patient is reintubated, select the postoperative event "Respiratory Failure" and do not select this element even if the reintubation ventilator support is > 48 hours. Ventilator support ends with the removal of the endotracheal tube or if the patient has a tracheostomy tube, until no longer ventilator dependent.

Indicate if the patient experienced pneumonia in the postoperative period. Pneumonia is defined as meeting three of five characteristics: fever (> 100.4 F or 38 C), leukocytosis, CXR with infiltrate, positive culture from sputum, or treatment with antibiotics.

Indicate whether the patient had acute renal failure or worsening renal function resulting in any of the following:

• New requirement for dialysis post-operatively
• Increase in serum creatinine level 3.0 x greater than baseline
• serum creatinine level ≥4 mg/dL , with an acute rise of at least 0.5 mg/dl

Indicate whether the patient was alive or dead at 30 days post-surgery (whether in the hospital or not).

time frame: 30days post-surgery

defined as an absolute increase in serum creatinine level C0.3 mg/dL, a 50% (1.5-fold) increase in serum creatinine level from baseline, or a reduction in urine output (documented oliguria< 0.5 mL/kg/h for 6h)