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Recruiting

NCT Number: NCT03925714

Impact of P53 and SIRT1 in Type 2 Diabetes

Investigating the impact of p53 and SIRT1 in the development of type 2 DM

Recruiting

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Key information

Conditions

DM

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 3

Primary location

About this study

Investigating the impact of p53 and SIRT1 in the development of type 2 DM through the treatment of prediabetic individuals by either nigetella salivata or Metformin

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Prediabetic subjects.

Exclusion criteria

  • Confirmed diabetes.
  • Hepatic or renal impairment.

Treatment and study plan

life style

Other

life sryle control only

Other names: life style management

metformin

Drug

metformin twice daily

Other names: cidophage

Nigetella salivata

Drug

NS twice daily

Other names: NS

Primary outcomes

  1. Number of patients with improved insulin resistance

    Time frame: 6 months

    Number of patients showing improved insulin resistance

Study contacts

Contact information is provided by the study sponsor or research team.

Sherief Abd-Elsalam, ass. prof.

CONTACT

[email protected]

00201147773440

Sponsors and collaborators

Lead sponsor

Sherief Abd-Elsalam

Other

Registry information

Official study title

Investigating the Impact of p53 and SIRT1 in the Development of Type 2 DM Through the Treatment of Prediabetic Individuals by Either Nigetella Salivata or Metformin

Important dates

Study start
2019
Primary completion
2028
Study completion
2028
First posted
Apr 24, 2019
Registry last updated
Apr 24, 2019

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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