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Completed

NCT Number: NCT06993519

Impact of Minimally Non-surgical Periodontal Treatment on Residual Pockets

A double-blind randomized-controlled clinical trial is conducted in order to evaluate the impact of non-surgical periodontal treatment by means of minimally invasive approach MINST or Q-SI (quadrantwise) approach in subjects with periodontitis on residual pockets after active periodontal treatment

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Key information

Conditions

Pocket, Periodontal Mouth Diseases Periodontal Diseases Periodontal Pocket Periodontitis Stomatognathic Diseases

Age range

18 year–75 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Policlinico G. Rodolico

Catania, 95124, Italy

About this study

A double-blind randomized-controlled clinical trial is conducted in order to evaluate the impact of non-surgical periodontal treatment in subjects with periodontitis. 60 patients: 30 with periodontitis and 30 healthy controls who underwent active periodontal treatment. All the patients are assessed for clinical, periodontal, blood following of minimally invasive approach MINST or Q-SI (quadrantwise).

Measurements are taken before and after initial periodontal treatment in the periodontal subjects in order to evaluate the best treatment for residual pockets.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Diagnosis of Periodontitis
  • Presence of residula periodontal pockets

Exclusion criteria

  • Periodontal treatment
  • Use of antibiotics, NSAIDs, and immunosuppressants during the last 6 months
  • Pregnancy

Treatment and study plan

Probin Pocket Depth reduction

Other

Probin Pocket Depth reduction in millimetres before and after treatment

Primary outcomes

  1. Probin Pocket Depth reduction

    Time frame: 1-year

    Probin Pocket Depth reduction in millimetres before and after treatment

Sponsors and collaborators

Lead sponsor

University of Catania

Other

Registry information

Official study title

Effects of Minimally Non-surgical Periodontal Treatment Versus Quadrantwise Subgingival Instrumentations on Residual Periodontal Pockets

Important dates

Study start
2021
Primary completion
2025
Study completion
2025
First posted
May 29, 2025
Registry last updated
May 29, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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