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OpenTrials
Completed

NCT Number: NCT06992219

Impact of Minimally Invasive Non-surgical Periodontal Treatment on Infrabony Defects

Fifty-two periodontitis patients (26 per group) were randomly assigned to the test (Minimally invasive non-surgical therapy - MINST) or the control group (Quadrantwise Subgingival Instrumentation - Q-SI) NPT protocols.

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Key information

Conditions

Periodontal Intrabony Defect Mouth Diseases Periodontal Diseases Periodontitis Stomatognathic Diseases

Age range

18 year–75 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

AOU Policlinico G. Rodolico

Catania, 95124, Italy

About this study

Clinical periodontal parameters, the number of pocket sites, x-ray of the infrabony defects characteristics and a composite outcome measure (COM) on the combined assessment of intrabony defect were recorded at baseline, and -3, 6- and at 12-months after treatment

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Diagnosis of Periodontitis

Exclusion criteria

  • Periodontal treatment
  • Use of antibiotics, NSAIDs, and immunosuppressants during the last 6 months
  • Pregnancy

Treatment and study plan

Non surgical periodontal treatment evaluated through probing pocket depth reduction

Other

Patients were treated with Minimally invasive non surgical treatment (MINST) or quadrant-subgingival instrumentation (Q-SI). The efficacy of treatment in both groups was evaluated through Probin Pocket Depth reduction in millimetres measurement before and after treatment.

Primary outcomes

  1. Probing Pocket Depth Reduction

    Time frame: 1-year

    Probing Pocket Depth Reduction in Probing Pocket Depth after treatment

Sponsors and collaborators

Lead sponsor

University of Catania

Other

Registry information

Official study title

Effects of Minimally Non-surgical Periodontal Treatment Versus Quadrantwise Subgingival Instrumentations on Infrabony Defects and Analysis of Defect Morphology on the Effectiveness of Treatment

Acronym: Infra-MINST

Important dates

Study start
2022
Primary completion
2024
Study completion
2024
First posted
May 28, 2025
Registry last updated
May 28, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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