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NCT Number: NCT06699732

Impact of Mindful Self-Compassion Therapy on Self Harm Behaviors, Emotional Regulation and Quality of Life Among Patients With Borderline Personality Disorder

The primary purpose of the study is to investigate whether Mindful Self-Compassion (MSC) therapy can significantly reduce self-harm behaviors, improve emotional regulation, and enhance the quality of life in individuals diagnosed with Borderline Personality Disorder (BPD). The study aims to contribute to the existing literature by providing robust evidence on the efficacy of MSC therapy for BPD, which could inform clinical practices and improve treatment outcomes

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Key information

Conditions

Psychological Distress Behavior Behavioral Symptoms Borderline Personality Disorder Borderline Personality Disorder (BPD) Emotional Regulation Mental Disorders Personality Disorders Quality of Life (QOL) Self Harm Self-Control Self-Injurious Behavior Social Behavior

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Commandant Afimh, Rawalpindi, Punjab Province, Pakistan

About this study

The current quantitative study will be carried out in two phases. A cross-sectional survey will assess quality of life, emotional regulation, psychological distress, self-harm behaviors, social support, and state of mindfulness during the first phase. A randomized controlled trial (RCT) will be done during the second phase where patients with Borderline Personality Disorder who are identified with psychological distress, low level of social support, and quality of life, will be categorized into two groups i.e. waitlist control group and intervention group through the process of randomization. Then Mindful Self Compassion therapy would be applied to participants in the intervention group. The control group is the waitlist control group so initially no intervention will be given to participants in the control group but the intervention will be given to the control group participants once the study is completed. The Mindful Self Compassion therapy would be implemented on participants using individual and in-person modes. The pre-and post-assessment will be done at Times 1 and 2 within and between control and interventional groups. After doing post-assessment the difference between pre and post-assessment will be compared to explore the efficacy of Mindful Self Compassion Therapy in patients with borderline personality.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

1. First time diagnosed non-hospitalized patients of Borderline Personality Disorder.

Patients of Borderline Personality Disorder experiencing psychological distress,low level of quality of life, social support, emotional dysregulation would be included.

Borderline Personality Disorder patients with age 18 years and above (both gender) from outpatient department (OPD) 4. Borderline personality patients who would be able to understand Urdu language and can give the informed consent
Exclusion criteria

The study would have the following exclusion criteria:

Hospitalized patients of Borderline Personality
Patients with Borderline Personality having other chronic co-morbid diseases such as cancer, cognitive deficits, and other chronic psychological disorders.
Patients with Borderline Personality younger than 18 years of age

Treatment and study plan

Mindful Self Compassion Therapy

Behavioral

Mindful Self-Compassion (MSC) therapy is an 8-week program blending mindfulness and self-compassion to improve emotional resilience and well-being.

Week 1: Introduction - Learn the basics of mindfulness, self-compassion, and reframing self-critical thoughts with kindness.

Week 2: Mindfulness - Practice observing thoughts and emotions without judgment to build self-awareness.

Week 3: Self-Kindness - Develop skills to treat yourself with warmth and care during difficult times.

Week 4: Common Humanity - Explore shared human experiences to reduce feelings of isolation.

Week 5: Working with Challenges - Learn strategies to respond compassionately to emotional pain.

Week 6: Growing Compassion - Deepen compassion for yourself and others through guided exercises.

Week 7: Resilience Building - Strengthen coping skills and foster emotional flexibility.

Week 8: Integration - Consolidate skills to maintain self-compassion in daily life.

Primary outcomes

World Health Organization Quality of Life Scale Urdu Version

Time frame: 3 months

It has 26 items and four domains: physical health (7 items), psychological health (6 items), social relationships (3 items), and environmental health (8 items); it also contains quality of life and general health items. The minimum value is 26 and the maximum value is 130. Higher scores on the scale indicate higher quality of life and low scores indicate low quality of life.

Study contacts

Contact information is provided by the study sponsor or research team.

Asma Mansoor, PhD Scholar

CONTACT

[email protected]

+923365374633

Sajida Naz, PhD

CONTACT

[email protected]

+923235493535

Sponsors and collaborators

Lead sponsor

Fatima Jinnah Women University

Other

Registry information

Official study title

Impact of Mindful Self-Compassion Therapy on Self Harm Behaviors, Emotional Regulation and Quality of Life Among Patients With Borderline Personality Disorder: A Randomized Controlled Trial

Important dates

Study start: 2024
Primary completion: 2025
Study completion: 2025
First posted: Nov 21, 2024
Registry last updated: Sep 2, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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