Impact of Microparticles on Postoperative Complications in Surgical Patients

Microparticles are cellular fragments which are released actively or passively under conditions of inflammation and stress. The impact of surgical operations on quantity and quality of microparticles remains unknown. In this observatory study we investigate quantitative and qualitative aspects of microparticles during cardiac and abdominal operations.

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Key information

Conditions

Neoplasm, Hepatic Colonic Diseases Colorectal Neoplasms Digestive System Diseases Digestive System Neoplasms Endocrine Gland Neoplasms Endocrine System Diseases Gastrointestinal Diseases Gastrointestinal Neoplasms Intestinal Diseases Intestinal Neoplasms Liver Diseases Liver Neoplasms Neoplasms Neoplasms by Site Pancreatic Diseases Pancreatic Neoplasms Rectal Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Department of visceral and transplant surgery, Bern University Hospital

Bern, 3010, Switzerland

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patients undergoing cardiac or abdominal operations with a minimum expected operative time of 2 hours

Exclusion criteria

Laparoscopic operations
emergency operations

Treatment and study plan

Primary outcomes

Postoperative morbidity

Time frame: 30 days

Secondary outcomes

Hospital stay

Time frame: 30 days
Mortality

Time frame: 30 days

Sponsors and collaborators

Lead sponsor

University of Bern

Other

Registry information

Official study title

The Impact of Microparticles on Inflammatory Responses During Visceral and Cardiac Surgery

Important dates

Study start: 2008
Primary completion: 2008
Study completion: 2010
First posted: May 15, 2008
Registry last updated: Sep 7, 2011

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed