Impact of Lung Function Prehabilitation to Postoperative Pulmonary Complications

The aim of this study is to compare the effect of lung function prehabilitation to postoperative pulmonary complications on patient undergoing upper abdominal surgery treated in intensive care unit.

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Key information

Conditions

Postoperative Pulmonary Complications (PPCs)

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

RSUPN dr. Cipto Mangunkusumo

Jakarta Pusat, Jakarta Special Capital Region, 10430, Indonesia

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

adults 18 years or older
scheduled for the upper abdominal surgery under general anesthesia with intraoperative mechanical ventilation
possess adequate cognitive function to comprehend and follow instructions
possess sufficient physical capacity to perform structured prehabilitation exercises
express willingness to participate in the intervention program before surgery

Exclusion criteria

pregnancy
pre-existing severe pulmonary diseases such as chronic obstructive pulmonary disease (COPD)
planned laparoscopic procedures
history of significant neuromuscular impairment (e.g: stroke)
declined to participate

Treatment and study plan

Lung Function Prehabilitation

Procedure

Participants assigned to the prehabilitation group received personalized exercise prescriptions, including aerobic training, muscle strengthening, and inspiratory muscle training with a threshold device. The prehabilitation program was conducted at the participants' homes for a minimum duration of two weeks. Adherence was monitored through logbook entries and video call evaluations to ensure correct implementation of the prescribed exercises.

Primary outcomes

Postoperative pulmonary complications

Time frame: Postoperative day 1 and 3

Including pulmonary infections, atelectasis, and diaphragmatic dysfunction. Pulmonary infection is assessed using the Clinical Pulmonary Infection Score (CPIS) and with a threshold of >6, atelectasis using Lung Ultrasound Score (LUS) of ≥1, and diaphragm ultrasound were used to evaluate diaphragm ratio. CPIS and LUS score assessments were conducted on postoperative day 1 and 3 by trained investigators, diaphragm ratio assessment was conducted preoperatively and on postoperative day 1 and 3, all findings were systematically recorded.

Sponsors and collaborators

Lead sponsor

Indonesia University

Other

Registry information

Official study title

The Impact of Lung Function Prehabilitation to Postoperative Pulmonary Complications on Patient Undergoing Upper Abdominal Surgery Treated in Intensive Care Unit: A Randomized Controlled Trial

Important dates

Study start: 2023
Primary completion: 2024
Study completion: 2024
First posted: Mar 6, 2025
Registry last updated: Mar 6, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed